NEWSLETTER
Tissue Antigens ( 1 9 7 7 ) ,9 , 69
Published by Munksgaard, Copenhagen, Denmark No part may be reproduced by any process without written permission from the author(s)
HLA in Temporal Arteritis J . Seignalet', C. Janbon', J . Sany', F. Janbon', J.M. Bidet', M. Brunel' , J . Jourdan' and J.L.. Bussiere*. Received for publication 30 August. accepted 6 September 1976
Twenty-six HLA antigens of the A and B arteritis. Our results are summarized in loci were tested in 61 unrelated Caucasoid Table 1. Temporal arteritis appears to be patients with temporal arteritis (Horton associated with HLA-B14. Polymyalgia disease) and in 300 healthy controls. In rheumatica seems related with HLAtemporal arteritis, only one significant Bw38 and HLA-B5. These data suggest modification was observed: the HLA- that polymyalgia rheumatica and temporal B14 increase - 22.95% against 8.67% in arteritis, even if they are often associated, are t w o distinct diseases. controls ( P = 0.002 and P c = 0.05). Among our 61 patients, 50 were inMore details concerning t h e results have vestigated for t h e presence of polymyalgia been submitted to the HLA and Disease rheumatica and were separated into two register in Copenhagen (Arne Svejgaard, groups (Table I). A comparison was made The Tissue Typing Laboratory, Rigsbetween these groups and 50 polymyalgia hospitalet, Blegdamsvej 9 , DK-2100 Kdbenrheumatica patients without temporal havn 0, Denmark). Table 1 Frequency of HLA-B14, HLA-BW38 and HLA-BS in Horton Disease and in Polymyalgia Rbeumatica
Number of patients Horton disease alone Horton disease & Pol ym yalgia rheurnatica Polyrnyalgia rheurnatica alone Healthy controls
HLA-B14
HLA-Bw38
HLA-BS
%
%
%
3.23
15.79
31
126,311
19 50
4 8.67
300
* Institut d'Hernatologie, Avenue Ernile Jeanbrau. 34000 Montpellier, France
115,791
m 5.33
p 2 6 3 . 1 ) 1241 13
Centre de Transfusion Sanguine, 30, Place Henri Dunant, 63000 Clermont-Ferrand, France.
Tissue Antigens ( 1 9 7 7 ) ,9 , 69
Published by Munksgaard, Copenhagen, Denmark No part may be reproduced by any process without written permission from the author(s)
HLA in Temporal Arteritis J . Seignalet', C. Janbon', J . Sany', F. Janbon', J.M. Bidet', M. Brunel' , J . Jourdan' and J.L.. Bussiere*. Received for publication 30 August. accepted 6 September 1976
Twenty-six HLA antigens of the A and B arteritis. Our results are summarized in loci were tested in 61 unrelated Caucasoid Table 1. Temporal arteritis appears to be patients with temporal arteritis (Horton associated with HLA-B14. Polymyalgia disease) and in 300 healthy controls. In rheumatica seems related with HLAtemporal arteritis, only one significant Bw38 and HLA-B5. These data suggest modification was observed: the HLA- that polymyalgia rheumatica and temporal B14 increase - 22.95% against 8.67% in arteritis, even if they are often associated, are t w o distinct diseases. controls ( P = 0.002 and P c = 0.05). Among our 61 patients, 50 were inMore details concerning t h e results have vestigated for t h e presence of polymyalgia been submitted to the HLA and Disease rheumatica and were separated into two register in Copenhagen (Arne Svejgaard, groups (Table I). A comparison was made The Tissue Typing Laboratory, Rigsbetween these groups and 50 polymyalgia hospitalet, Blegdamsvej 9 , DK-2100 Kdbenrheumatica patients without temporal havn 0, Denmark). Table 1 Frequency of HLA-B14, HLA-BW38 and HLA-BS in Horton Disease and in Polymyalgia Rbeumatica
Number of patients Horton disease alone Horton disease & Pol ym yalgia rheurnatica Polyrnyalgia rheurnatica alone Healthy controls
HLA-B14
HLA-Bw38
HLA-BS
%
%
%
3.23
15.79
31
126,311
19 50
4 8.67
300
* Institut d'Hernatologie, Avenue Ernile Jeanbrau. 34000 Montpellier, France
115,791
m 5.33
p 2 6 3 . 1 ) 1241 13
Centre de Transfusion Sanguine, 30, Place Henri Dunant, 63000 Clermont-Ferrand, France.
