Vol.

86,

No.

January

2,

BIOCHEMICAL

1979

AND

C5a-RELATED

SYNTHETIC

NEUTROPHIL Dennis

La

RESEARCH

COMMUNICATIONS Pages

HUMAN

From

BIOPHYSICAL

30, 1979

the

E.

Department

Jolla,

of

California

Received

Bruce

Molecular and

13,

1978

October

CHEMOTACTIC

Chenoweth,

92037

PEPTIDES

AS

FACTORS

W.

Erickson

Immunology,

and

Scripps

Rockefeller

227-234

Tony

Clinic

and

New

York,

University,

E.

Hugli

Research

Foundation,

New

York

10021

SUMMARY The

pentapeptide

mimics

the

L-methionyl-L-glutaminyl-l-leucyl-glycyl-L-arginine,

C-terminal

formylmethionyl

derivatives

simulate

C5a-related

chemotactic

of

or

of

their

C5a

receptor

on

with

Only

C5a

assessed

the

the

human

and

been

enzyme that

the

the

anaphylatoxin,

have

indicate of

interaction

peptide

activities.

structure

whit

Human C5a-related synthetic peptides as neutrophil chemotactic factors.

Vol. 86, No. January 2, BIOCHEMICAL 1979 AND C5a-RELATED SYNTHETIC NEUTROPHIL Dennis La RESEARCH COMMUNICATIONS Pages HUMAN From BIOPH...
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