Journal of Cerebral Blood Flow and Metabolism 11:502-507 © 1991 The International Society of Cerebral Blood Flow and Metabolism Published by Raven Press, Ltd., New York
Human Regional Cerebral Blood Flow During Rapid-Eye-Movement Sleep Peter Lund Madsen, S(Z>ren Holm, Sissel Vorstrup, Lars Friberg, Niels A. Lassen, and *Gordon Wildschi(Z>dtz Department of Clinical Physiology, Bispebjerg Hospital, Copenhagen, and *Sleep Laboratory, Department of Clinical Neurophysiology, University Hospital, Glostrup, Denmark
Summary: Owing to the coupling between CBP and neu ronal activity, regional CBP is a reflection of neural ac tivity in different brain regions. In this study we measured regional CBP during polysomnographically well-defined rapid-eye-movement (REM) sleep by the use of single photon emission computerized tomography and the new tracer 99mTc-dl-hexamethylpropyleneamine. Eleven healthy volunteers aged between 22 and 27 years were studied. CBP was measured on separate nights during REM sleep and during EEG-verified wakefulness. On awakening from REM sleep, all subjects reported visual dreams. During REM sleep CBP increased by 4% (p
Human Regional Cerebral Blood Flow During Rapid-Eye-Movement Sleep Peter Lund Madsen, S(Z>ren Holm, Sissel Vorstrup, Lars Friberg, Niels A. Lassen, and *Gordon Wildschi(Z>dtz Department of Clinical Physiology, Bispebjerg Hospital, Copenhagen, and *Sleep Laboratory, Department of Clinical Neurophysiology, University Hospital, Glostrup, Denmark
Summary: Owing to the coupling between CBP and neu ronal activity, regional CBP is a reflection of neural ac tivity in different brain regions. In this study we measured regional CBP during polysomnographically well-defined rapid-eye-movement (REM) sleep by the use of single photon emission computerized tomography and the new tracer 99mTc-dl-hexamethylpropyleneamine. Eleven healthy volunteers aged between 22 and 27 years were studied. CBP was measured on separate nights during REM sleep and during EEG-verified wakefulness. On awakening from REM sleep, all subjects reported visual dreams. During REM sleep CBP increased by 4% (p
