Tumor Biol. (2014) 35:11659–11666 DOI 10.1007/s13277-014-2504-x

RESEARCH ARTICLE

The preoperative lymphocyte to monocyte ratio predicts clinical outcomes in patients with stage II/III gastric cancer Xin Zhou & Yiping Du & Jun Xu & Zebo Huang & Tianzhu Qiu & Xiaping Wang & Jiaqi Qian & Wei Zhu & Ping Liu

Received: 17 April 2014 / Accepted: 13 August 2014 / Published online: 20 August 2014 # International Society of Oncology and BioMarkers (ISOBM) 2014

Abstract Recently, lymphocyte to monocyte ratio (LMR) has been reported to be associated with clinical outcomes in some types of cancer but has not been explored in gastric cancer. In this study, we analyzed the association between LMR and clinical outcomes in stage II/III gastric cancer patients. Preoperative LMR calculated from peripheral lymphocyte and monocyte with corresponding clinical features from 426 stage II/III gastric cancer patients was noted. Kaplan–Meier method and Cox regression model were applied for overall survival (OS) and recurrence-free survival (RFS). Related with smaller tumor size (p