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IMMUNE RESPONSE AFTER SPLENECTOMY HANS D. OCHS JOHN L. SULLIVAN GERALD SCHIFFMAN MARGARET R. HAMMERSCHLAG ELLIOT VICHINSKY JAMES MISER RALPH J. WEDGWOOD Division

of Arthritis and Immunology and Division of Hematology and Oncology, Department of Pediatrics, University of Washington and Children’s Orthopedic Hospital and Medical Center, Seattle, Washington,

and decreased

IgM levels have been reported in splenectomised functionally asplenic patients.4,5 These immunological findings are thought to be the basis for o.p.s.i., a major cause of which is Streptococcus pneumonice.1 In order to investigate the immune response in more and

have studied immune r sponses to an intraadministered antigen (bacteriophage

Immune response after splenectomy.

178 IMMUNE RESPONSE AFTER SPLENECTOMY HANS D. OCHS JOHN L. SULLIVAN GERALD SCHIFFMAN MARGARET R. HAMMERSCHLAG ELLIOT VICHINSKY JAMES MISER RALPH J. W...
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