Zhou et al. Chin J Cancer (2015) 34:34 DOI 10.1186/s40880-015-0026-6
Open Access
ORIGINAL ARTICLE
Incidence trends and age distribution of colorectal cancer by subsite in Guangzhou, 2000–2011 Qin Zhou, Ke Li, Guo‑Zhen Lin, Ji‑Chuan Shen, Hang Dong, Yu‑Ting Gu and Hua‑Zhang Liu*
Abstract Introduction: Colorectal cancer (CRC) is the third most common cancer in China. The incidence of CRC has been increasing in recent years. The aim of this study was to explore the incidence trends and the age distribution of CRC by subsite in Guangzhou between 2000 and 2011. Methods: A total of 22,432 incident cases of CRC between 2000 and 2011 from Guangzhou Cancer Registry were identified. Crude incidence and age-standardized rates (ASRs), using the Segi’s world standard population, were calculated for CRC and CRC subsites. The incidence trend was analyzed and the annual percentage change (APC) in incidence was calculated by using JoinPoint software. Results: The crude incidence increased significantly from 23.4/105 in 2000 to 37.4/105 in 2011 for males and from 20.9/105 to 30.5/105 for females. The ASRs of CRC incidence stabilized during the period of 2000–2011 for both males and females. The ages at the onset of CRC for both males and females during 2010–2011 were significantly higher compared with those during 2000–2002 (males: t = 1.95, P = 0.05; females: t = 6.03, P
Open Access
ORIGINAL ARTICLE
Incidence trends and age distribution of colorectal cancer by subsite in Guangzhou, 2000–2011 Qin Zhou, Ke Li, Guo‑Zhen Lin, Ji‑Chuan Shen, Hang Dong, Yu‑Ting Gu and Hua‑Zhang Liu*
Abstract Introduction: Colorectal cancer (CRC) is the third most common cancer in China. The incidence of CRC has been increasing in recent years. The aim of this study was to explore the incidence trends and the age distribution of CRC by subsite in Guangzhou between 2000 and 2011. Methods: A total of 22,432 incident cases of CRC between 2000 and 2011 from Guangzhou Cancer Registry were identified. Crude incidence and age-standardized rates (ASRs), using the Segi’s world standard population, were calculated for CRC and CRC subsites. The incidence trend was analyzed and the annual percentage change (APC) in incidence was calculated by using JoinPoint software. Results: The crude incidence increased significantly from 23.4/105 in 2000 to 37.4/105 in 2011 for males and from 20.9/105 to 30.5/105 for females. The ASRs of CRC incidence stabilized during the period of 2000–2011 for both males and females. The ages at the onset of CRC for both males and females during 2010–2011 were significantly higher compared with those during 2000–2002 (males: t = 1.95, P = 0.05; females: t = 6.03, P
