J Cardiovasc Thorac Res, 2015, 7(4), 149-153 doi: 10.15171/jcvtr.2015.32
TUOMS Publishing Group
http://journals.tbzmed.ac.ir/jcvtr
Original Article
Influence of Two Various Durations of Resistance Exercise on Oxidative Stress in the Male Rat’s Hearts Rafigheh Ghiasi1, Mustafa Mohammadi1*, Javad Ashrafi Helan2, Seied Raziallah Jafari Jozani2, Shima Mohammadi3, Akbar Ghiasi4, Roya Naderi5 Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran 3 Student of Pharmacy, Pharmacy School, Tabriz University of Medical Sciences, Tabriz, Iran 4 Faculty of Management, Zabol University of Medical Sciences, Zabol, Iran 5 Department of Physiology, Tabriz University of Medical Sciences, Tabriz, Iran 1 2
Article info Article History: Received: 19 November 2014 Accepted: 13 August 2015 epublished: 28 November 2015 Keywords: Resistance Exercise Oxidative Stress Duration of Exercise Rat
Abstract Introduction: The previous studies have suggested that alteration in oxidative stress and antioxidant defense depends on various factors, such as mode, intensity, frequency and duration of exercise. In this study, we compared the effects of two various durations of resistance exercise (1 month and 4 month) on oxidative stress and antioxidant status in cardiac tissue. Methods: Thirty Wistar male rats divided into 3 groups: control (sedentary), exercise-1 (regular exercise for 1 month) and exercise-2 group (regular exercise for 4 months). After the final to the experiment, the rats were anesthetized, and then blood and heart samples were obtained and used to determine glutathione peroxidase (GPX), superoxide dismutase (SOD), malondialdehyde (MDA) and biochemical estimation. Results: MDA levels between control and exercise-2 groups showed no significant difference, hence, MDA level in exercise-1 group was higher compared to control group (P
TUOMS Publishing Group
http://journals.tbzmed.ac.ir/jcvtr
Original Article
Influence of Two Various Durations of Resistance Exercise on Oxidative Stress in the Male Rat’s Hearts Rafigheh Ghiasi1, Mustafa Mohammadi1*, Javad Ashrafi Helan2, Seied Raziallah Jafari Jozani2, Shima Mohammadi3, Akbar Ghiasi4, Roya Naderi5 Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran 3 Student of Pharmacy, Pharmacy School, Tabriz University of Medical Sciences, Tabriz, Iran 4 Faculty of Management, Zabol University of Medical Sciences, Zabol, Iran 5 Department of Physiology, Tabriz University of Medical Sciences, Tabriz, Iran 1 2
Article info Article History: Received: 19 November 2014 Accepted: 13 August 2015 epublished: 28 November 2015 Keywords: Resistance Exercise Oxidative Stress Duration of Exercise Rat
Abstract Introduction: The previous studies have suggested that alteration in oxidative stress and antioxidant defense depends on various factors, such as mode, intensity, frequency and duration of exercise. In this study, we compared the effects of two various durations of resistance exercise (1 month and 4 month) on oxidative stress and antioxidant status in cardiac tissue. Methods: Thirty Wistar male rats divided into 3 groups: control (sedentary), exercise-1 (regular exercise for 1 month) and exercise-2 group (regular exercise for 4 months). After the final to the experiment, the rats were anesthetized, and then blood and heart samples were obtained and used to determine glutathione peroxidase (GPX), superoxide dismutase (SOD), malondialdehyde (MDA) and biochemical estimation. Results: MDA levels between control and exercise-2 groups showed no significant difference, hence, MDA level in exercise-1 group was higher compared to control group (P
