Acta Neurochir (2014) 156:1753–1760 DOI 10.1007/s00701-014-2161-2
CLINICAL ARTICLE - VASCULAR
Intraoperative assessment of cortical perfusion by indocyanine green videoangiography in surgical revascularization for moyamoya disease Haruto Uchino & Ken Kazumata & Masaki Ito & Naoki Nakayama & Satoshi Kuroda & Kiyohiro Houkin
Received: 10 April 2014 / Accepted: 12 June 2014 / Published online: 28 June 2014 # Springer-Verlag Wien 2014
Abstract Background Postoperative hyperperfusion is a potential complication of the direct bypass procedure for moyamoya disease (MMD). However, no reliable modality is available yet for the prediction of postoperative hyperperfusion during surgery for MMD. This study aimed to investigate whether semiquantitative analysis of indocyanine green (ICG) videoangiography could contribute to the prediction of postoperative hyperperfusion in MMD. Methods This study included 12 hemispheres from 10 patients who underwent surgical revascularization for MMD. Intraoperative ICG videoangiography was performed before and after a direct bypass procedure. The ICG intensity-time curves were semiquantitatively analyzed to evaluate cortical perfusion by calculating the blood flow index (BFI). Using single-photon emission computed tomography (SPECT), postoperative cerebral blood flow measurements were performed thrice: immediately, and 2 and 7 days after surgery. Results BFI significantly increased from 21.3±10.5 to 38.4± 20.0 after bypass procedures in all the hemispheres (p
CLINICAL ARTICLE - VASCULAR
Intraoperative assessment of cortical perfusion by indocyanine green videoangiography in surgical revascularization for moyamoya disease Haruto Uchino & Ken Kazumata & Masaki Ito & Naoki Nakayama & Satoshi Kuroda & Kiyohiro Houkin
Received: 10 April 2014 / Accepted: 12 June 2014 / Published online: 28 June 2014 # Springer-Verlag Wien 2014
Abstract Background Postoperative hyperperfusion is a potential complication of the direct bypass procedure for moyamoya disease (MMD). However, no reliable modality is available yet for the prediction of postoperative hyperperfusion during surgery for MMD. This study aimed to investigate whether semiquantitative analysis of indocyanine green (ICG) videoangiography could contribute to the prediction of postoperative hyperperfusion in MMD. Methods This study included 12 hemispheres from 10 patients who underwent surgical revascularization for MMD. Intraoperative ICG videoangiography was performed before and after a direct bypass procedure. The ICG intensity-time curves were semiquantitatively analyzed to evaluate cortical perfusion by calculating the blood flow index (BFI). Using single-photon emission computed tomography (SPECT), postoperative cerebral blood flow measurements were performed thrice: immediately, and 2 and 7 days after surgery. Results BFI significantly increased from 21.3±10.5 to 38.4± 20.0 after bypass procedures in all the hemispheres (p
