Bririrh Journal of Urology (1979), 51, 321
Inverted Papilloma in a 14-Year-Old Male Case Report A 14-year-old male presented with painless, gross, total haematuria. Five years earlier he had had a right nephroureterectomy because of the destructive effects of infection and reflux. Cystoscopy revealed a polypoid, fleshy, pink tumour hanging from the dome of the bladder, just to the right of the midline. The tumour was resected transurethrally and its base fulgurated. Repeat cystoscopies over 2 years have revealed no evidence of tumour recurrence. The specimen removed weighed 4.8 g. Microscopically, the surface of the tumour was covered by a slightly hyperplastic but smooth epithelial surface. The bulk of the tumour was composed of broad sheets of stratified epithelial cells and anastomosing cords of varying thickness. The component cells were generally regular in size and mitosis was not a notable feature. The outer layer of cells in the tumour cords was cuboidal,
Fig. 2 Component cells are regular; microcysts are present. (H and E x 250.)
with a palisading effect in some areas. There was a relatively scant, intervening, fibrovascular stroma. and a slight degree of inflammatory infiltrate was present. Microcysts were present in the tumour and some contained a homogeneous eosinophilic material. The cysts were lined by flattened cuboidal cells (Figs. 1 and 2).
Comment Inverted papilloma was described first by Potts and Hirst in 1963, and by several authors since then. The largest series was reported by Cameron and Lupton in 1976. T h e present case is unique because of its occurrence in a 14-year-old male a n d because of its location on t h e d o m e o f the bladder.
References Cameron, K. M. and Lupton, C. H. (1976). Inverted papilloma of the lower urinary tract. British Journal of Urology, 48. 561-571.
Potts, 1. F. and Hirst, E. (1963). Inverted papilloma of the bladder. Journal of Urology, 90, 175-179.
The Author Fig. 1 Hyperplastic surface epithelium with underlying tumour in a scant fibrovascular stroma. (H and E X 100.)
R. R. Francis, Division of Urology, Royal Alexandra Hospital, Edmonton, Alberta, Canada.
327
Inverted Papilloma in a 14-Year-Old Male Case Report A 14-year-old male presented with painless, gross, total haematuria. Five years earlier he had had a right nephroureterectomy because of the destructive effects of infection and reflux. Cystoscopy revealed a polypoid, fleshy, pink tumour hanging from the dome of the bladder, just to the right of the midline. The tumour was resected transurethrally and its base fulgurated. Repeat cystoscopies over 2 years have revealed no evidence of tumour recurrence. The specimen removed weighed 4.8 g. Microscopically, the surface of the tumour was covered by a slightly hyperplastic but smooth epithelial surface. The bulk of the tumour was composed of broad sheets of stratified epithelial cells and anastomosing cords of varying thickness. The component cells were generally regular in size and mitosis was not a notable feature. The outer layer of cells in the tumour cords was cuboidal,
Fig. 2 Component cells are regular; microcysts are present. (H and E x 250.)
with a palisading effect in some areas. There was a relatively scant, intervening, fibrovascular stroma. and a slight degree of inflammatory infiltrate was present. Microcysts were present in the tumour and some contained a homogeneous eosinophilic material. The cysts were lined by flattened cuboidal cells (Figs. 1 and 2).
Comment Inverted papilloma was described first by Potts and Hirst in 1963, and by several authors since then. The largest series was reported by Cameron and Lupton in 1976. T h e present case is unique because of its occurrence in a 14-year-old male a n d because of its location on t h e d o m e o f the bladder.
References Cameron, K. M. and Lupton, C. H. (1976). Inverted papilloma of the lower urinary tract. British Journal of Urology, 48. 561-571.
Potts, 1. F. and Hirst, E. (1963). Inverted papilloma of the bladder. Journal of Urology, 90, 175-179.
The Author Fig. 1 Hyperplastic surface epithelium with underlying tumour in a scant fibrovascular stroma. (H and E X 100.)
R. R. Francis, Division of Urology, Royal Alexandra Hospital, Edmonton, Alberta, Canada.
327
