Cancer Letters, 2 (t977) 195--200 © Elsevier/North-Holland Scientific Publishers Ltd. ,,
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ZARYOLOaY OFA
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C0LO ,T CCARCINOMA (QW-a.giS RL.. LY
XENOGRAFTED tN HAMSTERS AND IN NUDE MICE DAVID M, GOLDENBERG, ROSE A. PAVIA and LINDA SMITH Division of ExperimentaI Pathology, Department of Pathology, University of Kentuct~y Medical Center, Lexington, Kentucky 40506 (U.S.A.) (Received 18 August 1974~) (Revised version received 22 September 1'9761
SUMMARY
A karyological analysis of the G-banded chromosomes of the serially transplantable GW.39 human, colonic carcinoma was undertaken. GW-39 cells harvested from hamsters, nude (athymic) mice and cell cultures from 1972 tto 1976 revealed a hypod[ploid stemhne of 45 human chromosomes with a consistent loss of a 21-chrornosome. No apparent alterations of the near
.
.
.
,,
, .
,
,
ZARYOLOaY OFA
195
',
,
'
:,
:
':.
.
,
. .
,
C0LO ,T CCARCINOMA (QW-a.giS RL.. LY
XENOGRAFTED tN HAMSTERS AND IN NUDE MICE DAVID M, GOLDENBERG, ROSE A. PAVIA and LINDA SMITH Division of ExperimentaI Pathology, Department of Pathology, University of Kentuct~y Medical Center, Lexington, Kentucky 40506 (U.S.A.) (Received 18 August 1974~) (Revised version received 22 September 1'9761
SUMMARY
A karyological analysis of the G-banded chromosomes of the serially transplantable GW.39 human, colonic carcinoma was undertaken. GW-39 cells harvested from hamsters, nude (athymic) mice and cell cultures from 1972 tto 1976 revealed a hypod[ploid stemhne of 45 human chromosomes with a consistent loss of a 21-chrornosome. No apparent alterations of the near
