Left Ventricular Function in Chronic Pulmonary Hypertension
HANS P. KRAYENBUEHL, MD JURAJ TURINA, MD OTTO HESS, MD Zurich, Switzerland
From the Department of Internal Medicine, Medical Policlinic, Cardiology, University of Zurich, Zurich, Switzerland. This work was supported by a grant from the Swiss National Science Foundation. Manuscript received August 16, 1977; revised manuscript received December 27, 1977. accepted January 3, 1978. Address for reprints: H. P. Krayenbuehl, MD, Medical Policlinic, Cardiology, Raemistrasse 100, 8091 Zurich, Switzerland.
1150
June 1978
Ten patients, all women, with chronic pulmonary hypertension consequent to primary or secondary pulmonary vascular disease were studied with left ventricular micromanometry and cineangiography. Twelve subjects (eight women, four men) with atypical chest pain or a functional murmur served as control subjects. At rest, maximal velocity of contractile element shortening (Vmax), determined from left ventricular total pressure-veloctty curves and volumetric measurements derived from right anterior oblique cineangiograms, did not dtffer significantly between the two groups. Left ventricular end-diastolic pressure was significantly (P
HANS P. KRAYENBUEHL, MD JURAJ TURINA, MD OTTO HESS, MD Zurich, Switzerland
From the Department of Internal Medicine, Medical Policlinic, Cardiology, University of Zurich, Zurich, Switzerland. This work was supported by a grant from the Swiss National Science Foundation. Manuscript received August 16, 1977; revised manuscript received December 27, 1977. accepted January 3, 1978. Address for reprints: H. P. Krayenbuehl, MD, Medical Policlinic, Cardiology, Raemistrasse 100, 8091 Zurich, Switzerland.
1150
June 1978
Ten patients, all women, with chronic pulmonary hypertension consequent to primary or secondary pulmonary vascular disease were studied with left ventricular micromanometry and cineangiography. Twelve subjects (eight women, four men) with atypical chest pain or a functional murmur served as control subjects. At rest, maximal velocity of contractile element shortening (Vmax), determined from left ventricular total pressure-veloctty curves and volumetric measurements derived from right anterior oblique cineangiograms, did not dtffer significantly between the two groups. Left ventricular end-diastolic pressure was significantly (P
