1212 cent of a

polypeptide-secreting tumour, are not associated with significant abnormalitv of the gut endocrine svstem. S. N. JOFFE University Department of Surgery, D. W. SHORT Royal Infirmary, Glasgow.

anv

S. R. BLOOM JULIA POLAK

Royal Postgraduate Medical School, London.

patients with pneumoconiosis should be regarded as a specialrisk group where infection is likely to linger on. Symptoms which normally would lead to referral to a specialist are too often, and understandably, attributed to "pneumoconiosis", so a source

of infection may remain undetected.

Pindar Oaks Chest Clinic, Barnsley S70 4PN, and Wathwood Hospital,

Wath-on-Dearne,

ROSETTE-FORMING LYMPHOCYTES IN CERVICAL IN-SITU CARCINOMA I

SIR,-A depression in the percentage of E-rosette-forming lymphocytes in the peripheral blood has been reported in patients with lung cancer,’ cancer of the colon2 and a variety of other solid tumours.3 We have studied 20 consecutive patients with carcinoma-in-situ of the cervix, all of whom showed a consistent, significant (p