Thank you for your interest in our work. We note you are concerned about random differences in the baseline characteristics of patients in the REDOXS trials between the different groups. We have already addressed this issue in a letter published in the New England Journal of Medicine,1 and we plan to publish a secondary analysis that demonstrated similar results after adjusting for all the baseline characteristics in question.
Reference 1. Heyland DK, Wischmeyer P, Day AG. The role of glutamine supplementation in critical illness given the results of the REDOXS Study. Reply letter. New Engl J Med. In press.
Daren K. Heyland Rupinder Dhaliwal Kingston General Hospital, Kingston, ON, Canada
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