The New England Journal of Medicine Downloaded from nejm.org at UW-Madison on September 9, 2014. For personal use only. No other uses without permission. Copyright © 1991 Massachusetts Medical Society. All rights reserved.

The New England Journal of Medicine Downloaded from nejm.org at UW-Madison on September 9, 2014. For personal use only. No other uses without permission. Copyright © 1991 Massachusetts Medical Society. All rights reserved.

The New England Journal of Medicine Downloaded from nejm.org at UW-Madison on September 9, 2014. For personal use only. No other uses without permission. Copyright © 1991 Massachusetts Medical Society. All rights reserved.

The New England Journal of Medicine Downloaded from nejm.org at UW-Madison on September 9, 2014. For personal use only. No other uses without permission. Copyright © 1991 Massachusetts Medical Society. All rights reserved.

Linkage of a gene causing familial amyotrophic lateral sclerosis to chromosome 21 and evidence of genetic-locus heterogeneity.

Amyotrophic lateral sclerosis is a progressive neurologic disorder that commonly results in paralysis and death. Despite more than a century of resear...
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