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doi:10.1111/jpc.12935

ORIGINAL ARTICLE

Low vitamin D is associated with hypertension in paediatric obesity Kung-Ting Kao,1,2,3 Nobia Abidi,4 Sanjeeva Ranasinha,5 Justin Brown,4,6 Christine Rodda,3,4,7 Zoe McCallum,1,3 Margaret Zacharin,1,2,3 Peter J Simm,1,2,6, Costan G Magnussen8,9 and Matthew A Sabin1,2,3,4 1

Department of Endocrinology and Diabetes, The Royal Children’s Hospital, and 2Center for Hormone Research, Murdoch Childrens Research Institute, and Department of Paediatrics, University of Melbourne, and 4Department of Paediatrics, and 5School of Public Health and Preventive Medicine, Monash University, and 6Department of Paediatric Endocrinology and Diabetes, Monash Children’s Hospital, and 7Western Centre for Health Research, Sunshine Hospital, Melbourne, Victoria, and 8Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia and 9Research Centre of Applied and Preventative Cardiovascular Medicine, University of Turku, Turku, Finland 3

Aim: The aim of this paper was to investigate the relationship between circulating 25-hydroxyvitamin D (25(OH)D) and cardio-metabolic risk factors in a large cohort of obese youth attending tertiary paediatric obesity services. Methods: We conducted a retrospective cross-sectional study. Data were retrospectively collected from all new consultations of children and adolescents attending obesity outpatient clinics between 2008 and 2011 at the two major paediatric hospitals in Melbourne, Australia. Information collected included demographics, anthropometry, blood pressure, pubertal staging, body composition and fasting serum levels of 25(OH)D, glucose, insulin, cholesterol, triglyceride, high-density lipoprotein, liver function, calcium and phosphate. Results: 25(OH)D data were available in 229 patients (age 3–18 years; 116 men; mean (standard deviation) body mass index ( BMI) Z-score 2.5 (0.5) ). One hundred four (45%) participants were 25(OH)D deficient (

Low vitamin D is associated with hypertension in paediatric obesity.

The aim of this paper was to investigate the relationship between circulating 25-hydroxyvitamin D (25(OH)D) and cardio-metabolic risk factors in a lar...
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