ORIGINAL RESEARCH
Lower Extremity Peripheral Artery Disease and Quality of Life Among Older Individuals in the Community Aozhou Wu, MHS; Josef Coresh, MD, PhD; Elizabeth Selvin, PhD; Hirofumi Tanaka, PhD; Gerardo Heiss, MD, PhD; Alan T. Hirsch, MD; Bernard G. Jaar, MD, MPH; Kunihiro Matsushita, MD, PhD
Background-—Evidence regarding the association of lower extremity peripheral arterial disease with quality of life (QOL) is mainly from selected clinical populations or relatively small clinical cohorts. Thus, we investigated this association in community-derived populations. Methods and Results-—Using data of 5115 participants aged 66 to 90 years from visit 5 (2011-2013) of the Atherosclerosis Risk in Communities Study, we quantified the associations of ankle-brachial index (ABI) with several QOL parameters, including 12-item Short-Form Health Survey (SF-12), after accounting for potential confounders using linear and logistic regression models. Peripheral arterial disease defined by an ABI
Lower Extremity Peripheral Artery Disease and Quality of Life Among Older Individuals in the Community Aozhou Wu, MHS; Josef Coresh, MD, PhD; Elizabeth Selvin, PhD; Hirofumi Tanaka, PhD; Gerardo Heiss, MD, PhD; Alan T. Hirsch, MD; Bernard G. Jaar, MD, MPH; Kunihiro Matsushita, MD, PhD
Background-—Evidence regarding the association of lower extremity peripheral arterial disease with quality of life (QOL) is mainly from selected clinical populations or relatively small clinical cohorts. Thus, we investigated this association in community-derived populations. Methods and Results-—Using data of 5115 participants aged 66 to 90 years from visit 5 (2011-2013) of the Atherosclerosis Risk in Communities Study, we quantified the associations of ankle-brachial index (ABI) with several QOL parameters, including 12-item Short-Form Health Survey (SF-12), after accounting for potential confounders using linear and logistic regression models. Peripheral arterial disease defined by an ABI
