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Archives of Environmental Health: An International Journal Publication details, including instructions for authors and subscription information: http://www.tandfonline.com/loi/vzeh20

Lung Function Consequences of Dust Exposure in Asbestos Cement Manufacturing Plants a

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Hans Weill MD , Morton M. Ziskind MD , Carmel Waggenspack MPH & Charles E. Rossiter MA a

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Pulmonary Disease Section, Department of Medicine , Tulane University School of Medicine , New Orleans

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MRC Pneumoconiosis Research Unit , Penarth , South Wales , United Kingdom Published online: 02 May 2013.

To cite this article: Hans Weill MD , Morton M. Ziskind MD , Carmel Waggenspack MPH & Charles E. Rossiter MA (1975) Lung Function Consequences of Dust Exposure in Asbestos Cement Manufacturing Plants, Archives of Environmental Health: An International Journal, 30:2, 88-97, DOI: 10.1080/00039896.1975.10666650 To link to this article: http://dx.doi.org/10.1080/00039896.1975.10666650

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Lung Function Consequences of Dust Exposure in Asbestos Cement Manufacturing Plants Hans Weill, MD; Morton M. Ziskind, MD; Carmel Waggenspack, MPH; Charles E. Rossiter, MA

A comprehemsive study of health effec~s associated with the mixed dust exposure in this im:lustry has included the collection of clinical, radiographic, lung fametien, and dust exposure data on 859 workers in two piants. Evidence is presented supporting a dose-response re!aUonship between indexes of dust exposure and lung function, similar to the previolJlsly reported relationship with exieni oi x-ray film changes using the ILO Ute classification. lung volumes and maximum expira~ory flow rates decrease in relation to inc~eas­ ing cumulative dust exposure while pul-

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t has been the aim of investigators studying the inorganic dust diseases to establish which methods of biologic monitoring are most sensitive in detecting the earliest changes of diffuse pulmonary involvement and measuring the progression of the disease over time. This objective can be realized through data collected from a carefully designed epidemiologic study of workers exposed to a wellcharacterized environment, which usually requires analysis of past and

Submitted for pUblication June 28, 1974; accepted Sept 18. From the Pulmonary Disease Section, Department of Medicine, Tulane University School of Medicine, New Orleans (Dr. Weill, Dr. Ziskind, and Ms. Waggenspack), and the MRC Pneumoconiosis Research Unit, Penarth, South Wales (Mr. Rossiter). Reprint requests to the Department of Medicine, Pulmonary Disease Section, Tulane University School of Medicine, 1700 Perdido St, New Orleans, LA 70112 (Dr. Weill).

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Arch Environ HealthlVol 30, Feb 1975

morllU}! difiusin91 capacity (Il)L) is not dust-dose related. Workers who had crocid(jlite exposure had smaller lung volumes, lower expiratory flow rates, !lind reduced ilL when comp~red with those homing only chrysoiile exposure. When ~he s~uclY' popuiatioUl is dhrided i!"1to ell:posuwe groups, data thus far analyzed $ugges~ that the chest x-ray film will reveal smali opacities illS E:!arly

Lung function consequences of dust exposure in asbestos cement manufacturing plants.

A comprehensive study of health effects associated with the mixed dust exposure in this industry has included the collection of clinical, radiographic...
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