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Computer Methods in Biomechanics and Biomedical Engineering Publication details, including instructions for authors and subscription information: http://www.tandfonline.com/loi/gcmb20

Microscale modelling in biomechanics and mechanobiology a

Helder C. Rodrigues Guest Editor a

Departamento de Engenharia Mecânica, Instituto Superior Tecnico Universidade de Lisboa Published online: 17 Dec 2013.

To cite this article: Helder C. Rodrigues Guest Editor (2014) Microscale modelling in biomechanics and mechanobiology, Computer Methods in Biomechanics and Biomedical Engineering, 17:1, 1-1, DOI: 10.1080/10255842.2014.870712 To link to this article: http://dx.doi.org/10.1080/10255842.2014.870712

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Computer Methods in Biomechanics and Biomedical Engineering, 2014 Vol. 17, No. 1, 1, http://dx.doi.org/10.1080/10255842.2014.870712

PREFACE

Downloaded by [University of North Carolina] at 11:38 13 November 2014

Microscale modelling in biomechanics and mechanobiology

This special issue of CMBBE is a collection of papers that were presented and discussed at the Scientific Workshop ‘Microscale Modelling in Biomechanics and Mechan­ obiology’, 30 May –1 June 2011, in Ericeira, Portugal. Recently we have witnessed remarkable progress in cellular level computational and experimental method­ ologies to characterise the micro-biological and biomechanical environment, namely cellular forces, cell mechanical properties and mechanical function of cells and organelles. Such methods offer the necessary basis for the development of multi-scale methodologies aimed at a better understanding of how cells function and biomechanically react to their environment and how this behaviour affects macro- or tissue-level biomechanical behaviour. In response to these advances, this scientific workshop addressed problems in Biomechanics and Mechanobiology with the objective of promoting the development of analysis capabilities at the cellular level to quantify its biomechanical environment and characterising its influence across scales, i.e. from cell to tissue levels. The workshop took a multidisciplinary approach involving leading researchers from a wide range of areas, namely biomechanics, applied mechanics, biophys­ ics, biology and material science, and brought together

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expertise in theoretical and computational modelling and experimental analysis to investigate multi-scale phenom­ ena related to the behaviour of biological materials and systems present in the human body. Attendees came from leading research groups in America, Asia and Europe, reflecting the field’s growing scientific interest and importance. The different presentations, describing the latest developments in these areas, lead to broad and instructive discussions on the grand challenges of multiscale modelling and scale bridging in Biomechanics and Mechanobiology and how to undertake them. Helder C. Rodrigues Departamento de Engenharia Mecaˆnica Instituto Superior Tecnico Universidade de Lisboa Guest Editor Note ‘An affine micro-sphere based constitutive model, accounting for junctional sliding, can capture F-actin network mechanics’ by Van Oosterwyck, Hans; Rodriguez, Jose Felix; Doblare, Manuel; Garcı´a-Aznar, Jose Manuel, was published in Computer Methods in Biomechanics and Biomedical Engin­ eering, issue 16.9.

Microscale modelling in biomechanics and mechanobiology.

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