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Minimally invasive aortic valve replacement: the Leipzig experience Sven Lehmann1*, Denis R. Merk1*, Christian D. Etz1, Joerg Seeburger1, Thomas Schroeter1, Andreas Oberbach1, Madlen Uhlemann2, Robert Hoellriegel2, Martin Haensig1, Sergey Leontyev1, Jens Garbade1, Martin Misfeld1, Friedrich W. Mohr1 1
Department of Cardiac Surgery, 2Department of Cardiology, Heart Center Leipzig, University of Leipzig, Leipzig, Germany
*These two authors contributed equally to the work. Correspondence to: Dr. Sven Lehmann. Herzzentrum Leipzig, Struempellstr. 39, 04289 Leipzig, Germany. Email: [email protected]. Background: Minimally invasive techniques are progressively challenging traditional approaches in
cardiothoracic surgery. Minimally invasive aortic valve replacement (AVR) has become a routine procedure at our institution. Methods: We retrospectively analyzed all patients undergoing minimally invasive isolated AVR between
January 2003 and March 2014, at our institution. Mean follow-up was 4.7±4.3 years (range: 0-18 years) and was 99.8% complete. Results: There were 1,714 patients who received an isolated minimally invasive AVR. The mean (± SD)
patient age was 65±12.8 years, ejection fraction 60%±12% and log EuroSCORE 5.3%±5.1%. Mean crossclamp time was 58±18 minutes and mean cardiopulmonary bypass (CPB) time was 82.9±26.7 minutes. Thirty-day survival was 97.8%±0.4%, and 69.4%±1.7% at 10-years. The multivariate analysis revealed age at surgery [P=0.016; odds ratio (OR), 1.1], length of surgery time (P=0.002; OR, 1.01), female gender (P=0.023; OR, 3.54), preoperative myocardial infarction (MI) (P=0.006; OR, 7.87), preoperative stroke (P=0.001; OR, 13.76) and preoperative liver failure (P=0.015; OR, 10.28) as independent risk factors for mortality. Coxregression analysis revealed the following predictors for long term mortality: age over 75 years (P
Minimally invasive aortic valve replacement: the Leipzig experience Sven Lehmann1*, Denis R. Merk1*, Christian D. Etz1, Joerg Seeburger1, Thomas Schroeter1, Andreas Oberbach1, Madlen Uhlemann2, Robert Hoellriegel2, Martin Haensig1, Sergey Leontyev1, Jens Garbade1, Martin Misfeld1, Friedrich W. Mohr1 1
Department of Cardiac Surgery, 2Department of Cardiology, Heart Center Leipzig, University of Leipzig, Leipzig, Germany
*These two authors contributed equally to the work. Correspondence to: Dr. Sven Lehmann. Herzzentrum Leipzig, Struempellstr. 39, 04289 Leipzig, Germany. Email: [email protected]. Background: Minimally invasive techniques are progressively challenging traditional approaches in
cardiothoracic surgery. Minimally invasive aortic valve replacement (AVR) has become a routine procedure at our institution. Methods: We retrospectively analyzed all patients undergoing minimally invasive isolated AVR between
January 2003 and March 2014, at our institution. Mean follow-up was 4.7±4.3 years (range: 0-18 years) and was 99.8% complete. Results: There were 1,714 patients who received an isolated minimally invasive AVR. The mean (± SD)
patient age was 65±12.8 years, ejection fraction 60%±12% and log EuroSCORE 5.3%±5.1%. Mean crossclamp time was 58±18 minutes and mean cardiopulmonary bypass (CPB) time was 82.9±26.7 minutes. Thirty-day survival was 97.8%±0.4%, and 69.4%±1.7% at 10-years. The multivariate analysis revealed age at surgery [P=0.016; odds ratio (OR), 1.1], length of surgery time (P=0.002; OR, 1.01), female gender (P=0.023; OR, 3.54), preoperative myocardial infarction (MI) (P=0.006; OR, 7.87), preoperative stroke (P=0.001; OR, 13.76) and preoperative liver failure (P=0.015; OR, 10.28) as independent risk factors for mortality. Coxregression analysis revealed the following predictors for long term mortality: age over 75 years (P
