Accepted Manuscript Minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis: Comparison between isthmic and degenerative spondylolisthesis Jong Yeol Kim, MD, Jeong Yoon Park, MD, PhD, Kyung Hyun Kim, MD, Sung Uk Kuh, MD, PhD, Dong Kyu Chin, MD, PhD, Keun Su Kim, MD, PhD, Yong Eun Cho, MD, PhD PII:
S1878-8750(15)00710-X
DOI:
10.1016/j.wneu.2015.06.003
Reference:
WNEU 2937
To appear in:
World Neurosurgery
Received Date: 25 March 2015 Revised Date:
1 June 2015
Accepted Date: 3 June 2015
Please cite this article as: Kim JY, Park JY, Kim KH, Kuh SU, Chin DK, Kim KS, Cho YE, Minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis: Comparison between isthmic and degenerative spondylolisthesis, World Neurosurgery (2015), doi: 10.1016/j.wneu.2015.06.003. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
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Highlights 1. Minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) for isthmic spondylolisthesis is still controversial. The purpose of this study is to compare between
2. The same MIS TLIF techniques were applied to both groups.
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isthmic spondylolisthesis (IS) and degenerative spondylolisthesis (DS) after MIS TLIF.
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3. MIS TLIF resulted in similar clinical outcomes both IS and DS, and disc height restoration
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was more effective for IS than DS,
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4. MIS TLIF can be a safe and effective surgical option for both IS and DS.
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Minimally
invasive
spondylolisthesis:
transforaminal
Comparison
lumbar
between
MIS TLIF for spondylolisthesis
interbody
isthmic
and
fusion
for
degenerative
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spondylolisthesis
Jong Yeol Kim, MD, Jeong Yoon Park, MD, PhD, Kyung Hyun Kim, MD, Sung Uk Kuh,
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MD, PhD, Dong Kyu Chin, MD, PhD, Keun Su Kim, MD, PhD, Yong Eun Cho, MD, PhD
Department of Neurosurgery, Gangnam Severance Hospital, Spine and Spinal Cord Institute,
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Yonsei University College of Medicine, Seoul, Republic of Korea
Corresponding author: Jeong Yoon Park, M.D., Ph.D.
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Department of Neurosurgery, Gangnam Severance Hospital, Spine and Spinal Cord Institute, Yonsei University College of Medicine, 211 Eonjuro, Gangnam-gu, Seoul, 135-720, Korea Tel: 82-2-2019-3390, Fax: 82-3-3461-9229
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E-mail:
[email protected] 1
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MIS TLIF for spondylolisthesis
Abstract
Introduction Minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) is a common surgical option for degenerative spondylolisthesis (DS). However, its effectiveness
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for isthmic spondylolisthesis (IS) is still controversial. No current studies have directly compared perioperative and postoperative results including various radiologic parameters
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between IS and DS after MIS TLIF.
Purpose The purpose of this study is to compare the clinical and radiologic results between
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isthmic and degenerative spondylolisthesis after MIS TLIF.
Methods This is a retrospective study of 41 patients who underwent MIS TLIF for single segment, grade 1 or 2 IS (n=18) and DS (n=23). The same surgical techniques and procedure were applied to both groups. Perioperative outcomes (operation time, blood loss, hospital stay,
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complications), clinical outcomes (VAS, ODI), radiologic parameters (disc height, degree of spondylolisthesis, slip angle, lumbar lordosis, segmental lordosis, sacro-pelvic parameters: pelvic incidence, sacral slope, pelvic tile) and fusion rates using CT scanning were compared
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between groups at 1 year postoperatively.
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Results There were no significantly different perioperative results between groups. Mean VAS and ODI scores significantly improved postoperatively in both groups, but were not significantly different between groups at each follow-up point. Radiologic parameters were not significantly different between groups except disc height and degree of spondylolisthesis. The disc heights were increased postoperatively (IS: 6.79 to 9.22 mm; DS: 8.18 to 8.97 mm) in both groups and there were significant differences preoperatively. In addition, disc height 2
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MIS TLIF for spondylolisthesis
restoration was greater for IS than DS (2.43 mm vs. 0.79 mm, p=0.01). However, postoperative disc heights were not significantly different between groups. The degree of spondylolisthesis was significantly different between groups both pre- (16.77 vs. 11.33%,
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p