ORIGINAL ARTICLE

Mitral valve regurgitation: accurate flow

quantification with

blood

MRI

J.J.M. Westenberg, J. Doornbos, J.J. Bax, M.G. Danilouchkine, R.J. van der Geest, G. Labadie, H.J. Lamb, M.I.M. Versteegh, A. de Roos, R-A.E. Dion, J.H.C. Reiber

Background. The quantification of transvalvular blood flow through the mitral valve (MV) and regurgitant flow in particular is difficult with echocardiography, which is the method of choice to diagnose patients selected for valve repair or replacement. With magnetic resonance imaging, information on the intraventricular blood flow can be obtained. Several scanning techniques have attempted to assess the regurgitant flow. These techniques either do not directly assess the complete flow through the MV, or they do not measure the flow at the location of the valve. Aim. To investigate the accuracy of a novel method using three-directional velocity-encoded MRI to acquire the transvalvular blood flow directly from the intraventricular blood flow field, also representing the regurgitant flow during systole. Methods. Ten volunteers without cardiac valvular disease were recruited. The transvalvular MV flow volume was measured with three-directional velocity-encoded MRI (3-dir MV flow). J.J.M. Westenberg J.H.C. Relber Division of Image Processing Department of Radiology, Leiden University Medical Centre, Leiden Interuniversity Cardiology Institute of the Netherlands, Utrecht J. Doombos G. Labadle H.J. Lamb A. de Roos Department of Radiology JJ. Bax Department of Cardiology M.G. Danilouchklne RJ. van der Geest Division of Image Processing Department of Radiology

M.I.M. Vetoeegh R.A.E. Dion Department of Cardio-Thoracic Surgery, Leiden University Medical Centre, Leiden

Correspondence to: J.H.C. Reiber Division of Image Processing, Department of Radiology, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA Leiden E-mail: [email protected]

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Results. The transvalvular flow measurements correlate very well with the flow measured in the aorta (rp=0.92, p

Mitral valve regurgitation: accurate blood flow quantification with MRI.

The quantification of transvalvular blood flow through the mitral valve (MV) and regurgitant flow in particular is difficult with echocardiography, wh...
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