JAW
1082
Vol
15. No. 5
April IWD:1082-6
OSAMU FUJIMURA, MD,” GEORGE J. KLEIN, MD, F RAYMOND YEE, MD, FRCP(C), FACC,t ARJUN D. S Lfwhgton,
Kentwhy;
Loniion.
Ontcrrio, Cflnah
nnd Sncramento.
in some patients c when it is assoction over the accessory sponse (1). However, the mechanism by which atrial fibrillation is initiated in the presence of the accessory pathway is not fully understood. It has been shown that preceding reciprocating tachycardia plays an important role in its genesis (i-4). bcl more recently, it has ken hypothesized that the accessory pathway itself may initiate atrial fibrillation by virtue of its From the *Section of Cafxhurqy. University of Kentucky Medicul Center. Lexingon. Kentucky: Qwdiac Investigation Unit. University Hos@ital, LQ&NI, Ontario, Cwda apid $3941 J Street. Suite 2% Sacmmentu. ~~i~~. This study was supported by the Heart and Stroke Foundation of T-to. e)ntario. Canada. Dr. Klein is a Distinguished Research Professor of the Heart and Stroke F0u~~ti~n. Drs. Yee and Sharma are Ontario Ministry vf He&h Career Scientists. ed June 13. 1989: revised manuscript received August lein. MD. University Hospital. 339
Califontia
~r~l~ite~t~re(5.6). To test this hypothesis, we assessed multiple intracardiac ele~tro~~ms at the onset of atrial e~e~tropbysiolo~i~studies in a la of patients with ventricular pre-excitation.
Study pn~e~~. The data from 547 consecutive patients with manifest ventricular pree-excitationwho were referred to our institution for elecarophysiologic studies were reviewed. Two patient groups were selecte follows. The atrial fibrillationgroup (n = 79) had atrial llation lasting 230 s ~ur~~~the course of the routine electropbys~olog~c study without any attempt to induce it intentionally with rapid atrial pacing. The control group (n = 53) consisted of those in whom atrial fibrillationcould e induced eve intentionallywith rapid atria1pacing. Patients were excluded from the control group if atrial fibrillation had been documented clinically. None of the patients in either group had 073s1097/w/$3.50
A=
herefore, ial sites recorded
ial ~~cti~atioa
x (C/PA interval).
we defined t
at the
lead
value
1082
Vol
15. No. 5
April IWD:1082-6
OSAMU FUJIMURA, MD,” GEORGE J. KLEIN, MD, F RAYMOND YEE, MD, FRCP(C), FACC,t ARJUN D. S Lfwhgton,
Kentwhy;
Loniion.
Ontcrrio, Cflnah
nnd Sncramento.
in some patients c when it is assoction over the accessory sponse (1). However, the mechanism by which atrial fibrillation is initiated in the presence of the accessory pathway is not fully understood. It has been shown that preceding reciprocating tachycardia plays an important role in its genesis (i-4). bcl more recently, it has ken hypothesized that the accessory pathway itself may initiate atrial fibrillation by virtue of its From the *Section of Cafxhurqy. University of Kentucky Medicul Center. Lexingon. Kentucky: Qwdiac Investigation Unit. University Hos@ital, LQ&NI, Ontario, Cwda apid $3941 J Street. Suite 2% Sacmmentu. ~~i~~. This study was supported by the Heart and Stroke Foundation of T-to. e)ntario. Canada. Dr. Klein is a Distinguished Research Professor of the Heart and Stroke F0u~~ti~n. Drs. Yee and Sharma are Ontario Ministry vf He&h Career Scientists. ed June 13. 1989: revised manuscript received August lein. MD. University Hospital. 339
Califontia
~r~l~ite~t~re(5.6). To test this hypothesis, we assessed multiple intracardiac ele~tro~~ms at the onset of atrial e~e~tropbysiolo~i~studies in a la of patients with ventricular pre-excitation.
Study pn~e~~. The data from 547 consecutive patients with manifest ventricular pree-excitationwho were referred to our institution for elecarophysiologic studies were reviewed. Two patient groups were selecte follows. The atrial fibrillationgroup (n = 79) had atrial llation lasting 230 s ~ur~~~the course of the routine electropbys~olog~c study without any attempt to induce it intentionally with rapid atrial pacing. The control group (n = 53) consisted of those in whom atrial fibrillationcould e induced eve intentionallywith rapid atria1pacing. Patients were excluded from the control group if atrial fibrillation had been documented clinically. None of the patients in either group had 073s1097/w/$3.50
A=
herefore, ial sites recorded
ial ~~cti~atioa
x (C/PA interval).
we defined t
at the
lead
value
