ONCOLOGY LETTERS 13: 3567-3571, 2017

Cisplatin regulates cell autophagy in endometrial cancer cells via the PI3K/AKT/mTOR signalling pathway QIONGYAN LIN1,2, YIFENG WANG1, DUNJIN CHEN2, XIUJIE SHENG2, JUAN LIU2 and HANZHEN XIONG2 1

Department of Gynaecology and Obstetrics, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510280; 2Department of Gynaecology and Obstetrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510150, P.R. China Received October 5, 2015; Accepted January 17, 2017 DOI: 10.3892/ol.2017.5894 Abstract. Endometrial cancer is the most common gynaecological malignancy encountered in developed countries and the second most common in the developing world. The five‑year survival rate of patients with endometrial cancer diagnosed at a late stage is 80% (3). However, the majority of cases of endometrial cancer are diagnosed at a later stage and the outcome is poor, with a five‑year survival rate of

mTOR signalling pathway.

Endometrial cancer is the most common gynaecological malignancy encountered in developed countries and the second most common in the developing world...
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