CLINICAL PATHOLOGIC CHALLENGE
Nasal Tumoral Lesion: Challenge Montserrat Molgó, MD,* Álvaro Abarzúa, MD,* Laura Giesen, MD,* and Sergio González, MD†
(Am J Dermatopathol 2015;37:405)
CASE REPORT A 67-year-old man with a history of smoking presented with a nasal growth, which had increased in size in the previous 2 months. The physical examination revealed an erythematous violaceous exophytic tumor located in the left nostril, diameter of 3 cm, with an ulcerated and friable surface (Fig. 1). A biopsy was performed, and the histopathological examination showed a superficial and ulcerated fragment of skin. In the dermis, there was a well-vascularized tumoral lesion. The neoplastic cells were epithelioid with a clear vacuolated cytoplasm and slight to moderate pleomorphism (Figs. 2, 3).
FIGURE 1. Erythematous-violaceous exophytic and ulcerated tumor on the left nostril.
FIGURE 2. Epithelioid clear cells with moderate pleomorphism embedded in a well vascularized stroma. HE, 400x.
FIGURE 3. Immunohistochemical staining showing a negative reaction for CD31 in tumor cells, 200x.
WHAT IS YOUR DIAGNOSIS? (Continued on page 423) From the Departments of *Dermatology, and †Pathology, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile. The authors declare no conflicts of interest. Reprints: Montserrat Molgó, MD, Department of Dermatology, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Vicuña Mackenna 4686, San Joaquín, Santiago 781 0000, Chile (e-mail: montsemolgo1@ gmail.com). Copyright © 2014 Wolters Kluwer Health, Inc. All rights reserved.
Am J Dermatopathol Volume 37, Number 5, May 2015
www.amjdermatopathology.com |
405
Copyright © 2015 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.
Nasal Tumoral Lesion: Challenge Montserrat Molgó, MD,* Álvaro Abarzúa, MD,* Laura Giesen, MD,* and Sergio González, MD†
(Am J Dermatopathol 2015;37:405)
CASE REPORT A 67-year-old man with a history of smoking presented with a nasal growth, which had increased in size in the previous 2 months. The physical examination revealed an erythematous violaceous exophytic tumor located in the left nostril, diameter of 3 cm, with an ulcerated and friable surface (Fig. 1). A biopsy was performed, and the histopathological examination showed a superficial and ulcerated fragment of skin. In the dermis, there was a well-vascularized tumoral lesion. The neoplastic cells were epithelioid with a clear vacuolated cytoplasm and slight to moderate pleomorphism (Figs. 2, 3).
FIGURE 1. Erythematous-violaceous exophytic and ulcerated tumor on the left nostril.
FIGURE 2. Epithelioid clear cells with moderate pleomorphism embedded in a well vascularized stroma. HE, 400x.
FIGURE 3. Immunohistochemical staining showing a negative reaction for CD31 in tumor cells, 200x.
WHAT IS YOUR DIAGNOSIS? (Continued on page 423) From the Departments of *Dermatology, and †Pathology, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile. The authors declare no conflicts of interest. Reprints: Montserrat Molgó, MD, Department of Dermatology, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Vicuña Mackenna 4686, San Joaquín, Santiago 781 0000, Chile (e-mail: montsemolgo1@ gmail.com). Copyright © 2014 Wolters Kluwer Health, Inc. All rights reserved.
Am J Dermatopathol Volume 37, Number 5, May 2015
www.amjdermatopathology.com |
405
Copyright © 2015 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.
