INTRODUCTION

New Concepts in Fillers Mitchel P. Goldman, MD*

The author has indicated no significant interest with commercial supporters.

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major effect of aging is the loss of facial volume through resorption of bone, muscle, and dermal tissue including fat. This near-universal occurrence in the nonmorbidly obese population is one of the root causes for sagging skin and deep wrinkles. Unlike photodamage and fine wrinkles, topical treatments including lasers and other high-energy sources (focused ultrasound and radiofrequency) are not appropriate or effective in reversing this effect. Surgical options on excising loose skin (face-lift) with a variety of techniques and marketing names result in an unnatural-appearing tautness to the skin. Reversing bone and muscle resorption is not yet available. Dermatologists and cosmetic surgeons have recognized the importance of reestablishing youthful volume to the skin through the use of dermal fillers. This special issue presents an analysis of a variety of dermal fillers beginning with an understanding of the mechanism of action and lifting potential of fillers in Basics of Dermal Filler Rheology, by Sébastien Pierre, Steven Liew, and Aude Bernardin, A Randomized, Evaluator-Blinded, Controlled Study of Effectiveness and Safety of Small Particle Hyaluronic Acid plus Lidocaine for Lip Augmentation and Perioral Rhytids by Kenneth Beer, Richard J. Glogau, Jeffrey S. Dover, Ava Shamban, Lata Handiwala, and Jason T. Olin, and Functional Safety Assessments Used in a Randomized, Controlled Study of Small Gel Particle Hyaluronic Acid for Lip Augmentation by Stacy R. Smith, Heather M. Vander Ploeg, Mary Sanstead, Craig D. Albright, Michael J. Theisen, and Xiaoming Lin,

which evaluates a newly FDA-approved version of an established filler for this specific localized area. Unique aspects of dermal fillers is evaluated in Ultrastructural Analysis of Three Hyaluronic Acid Softtissue Fillers Using Scanning Electron Microscopy by Timothy C. Flynn, David H. Thompson, Seok-Hee Hyun, and David J. Howell. Evaluating the thinking of our patients who request facial rejuvenation is evaluated in Facial Treatment Preferences in Aesthetically Aware Women by Vic Narurkar, Ava Shamban, Peter Sissins, and Conor Gallagher. The Use of Non-Traditional Fillers and Neuromodulators to Improve Patient Satisfaction by Allan Wirtzer further details nonphysical results of such treatment. And finally, Greg Goodman details an interesting reaction to a highand low-molecular-weight combination hyaluronic acid. We appreciate the support of our industry partners in bringing this useful information to print to better educate dermatologic surgeons on this growing field with the result of positioning our specialty as the thought leaders and experts in providing natural rejuvenation techniques to our aging population. We are indebted to the following companies whose generous support of dermatologic surgery education is deeply appreciated: Allergan, Inc., Merz Pharmaceuticals, Valeant Pharmaceuticals North America, LLC.

*Cosmetic Laser Dermatology, San Diego, California © 2015 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved. ISSN: 1076-0512 Dermatol Surg 2015;41:S119 DOI: 10.1097/DSS.0000000000000335

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© 2015 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.

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