however, do not have a significantly longer duration of PN in our multivariate analysis. The limitations of the study include a small sample size and the retrospective nature of the analysis.
accounted for the majority of cases. Patients with an atopic diathesis had a significantly lower median age of PN onset compared to patients without. A significant number of patients had underlying systemic causes, highlighting the need for systemic investigations in extensive PN.
Conclusions
All patients with extensive PN had identifiable causes in this study. A dermatological condition was the predominant etiology in both patients with monofactorial and multifactorial disease, of which endogenous eczema
Disclosure Statement The authors declare that no sponsorship or funding was received for the study and that there are no relevant conflicts of interest.
References 1 Hyde JN: Prurigo nodularis; in Hyde JN, Montgomery FH (eds): A Practical Treatise on Diseases of the Skin for the Use of Students and Practitioners, ed 8. Philadelphia, Lea and Febiger, 1909, pp 174–175. 2 Iking A, Grundmann S, Chatzigeorgakidis E, Phan NQ, Klein D, Ständer S: Prurigo as a symptom of atopic and non-atopic diseases: aetiological survey in a consecutive cohort of 108 patients. J Eur Acad Dermatol Venereol 2013;27:550–557. 3 Schelnitz LS, Paller AS: Hodgkin’s disease manifesting as prurigo nodularis. Pediatr Dermatol 1990;7:136–139.
4 Lee MR, Shumack S: Prurigo nodularis: a review. Australas J Dermatol 2005;46:211–218. 5 Dazzi C, Erma D, Piccinno R, Veraldi S, Caccialanza M: Psychological factors involved in prurigo nodularis: a pilot study. J Dermatolog Treat 2011;22:211–214. 6 Tanaka M, Aiba S, Matsumura N, Aoyama H, Tagami H: Prurigo nodularis consists of two distinct forms: early-onset atopic and late-onset non-atopic. Dermatology 1995; 190: 269– 276. 7 Rowland Payne CM, Wilkinson JD, McKee PH, Jurecka W, Black MM: Nodular prurigo – a clinicopathological study of 46 patients. Br J Dermatol 1985;113:431–439.
8 Hong WW, Ang LW, Cutter JL, James L, Chew SK, Goh KT: Changing seroprevalence of hepatitis B virus markers of adults in Singapore. Ann Acad Med Singapore 2010; 39: 591–598. 9 Perez GL, Peters MS, Reda AM, Butterfield JH, Peterson EA, Leiferman KM: Mast cells, neutrophils and eosinophils in prurigo nodularis. Arch Dermatol 1993;129:861–865. 10 Bonacini M: Pruritus in patients with chronic human immunodeficiency virus, hepatitis B and C virus infections. Dig Liver Dis 2000;32: 621–625.
Note to the Readers
The publisher is well aware of the special nature of the paper entitled ‘Diagnostic Features of Pemphigus vulgaris in Patients with Bullous Pemphigoid: Molecular Analysis of Autoantibody Profile’ by Sami et al. [Dermatology 2002;204:108–117, DOI: 10.1159/000051827]. Everything possible has been undertaken in order to correctly modify the authorship. However, due to various reasons this proved to be an impossible task. The publisher therefore decided that the authorship of this article needs to remain as it is.
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Dermatology 2014;228:276–280 DOI: 10.1159/000358250
Tan/Tey
accounted for the majority of cases. Patients with an atopic diathesis had a significantly lower median age of PN onset compared to patients without. A significant number of patients had underlying systemic causes, highlighting the need for systemic investigations in extensive PN.
Conclusions
All patients with extensive PN had identifiable causes in this study. A dermatological condition was the predominant etiology in both patients with monofactorial and multifactorial disease, of which endogenous eczema
Disclosure Statement The authors declare that no sponsorship or funding was received for the study and that there are no relevant conflicts of interest.
References 1 Hyde JN: Prurigo nodularis; in Hyde JN, Montgomery FH (eds): A Practical Treatise on Diseases of the Skin for the Use of Students and Practitioners, ed 8. Philadelphia, Lea and Febiger, 1909, pp 174–175. 2 Iking A, Grundmann S, Chatzigeorgakidis E, Phan NQ, Klein D, Ständer S: Prurigo as a symptom of atopic and non-atopic diseases: aetiological survey in a consecutive cohort of 108 patients. J Eur Acad Dermatol Venereol 2013;27:550–557. 3 Schelnitz LS, Paller AS: Hodgkin’s disease manifesting as prurigo nodularis. Pediatr Dermatol 1990;7:136–139.
4 Lee MR, Shumack S: Prurigo nodularis: a review. Australas J Dermatol 2005;46:211–218. 5 Dazzi C, Erma D, Piccinno R, Veraldi S, Caccialanza M: Psychological factors involved in prurigo nodularis: a pilot study. J Dermatolog Treat 2011;22:211–214. 6 Tanaka M, Aiba S, Matsumura N, Aoyama H, Tagami H: Prurigo nodularis consists of two distinct forms: early-onset atopic and late-onset non-atopic. Dermatology 1995; 190: 269– 276. 7 Rowland Payne CM, Wilkinson JD, McKee PH, Jurecka W, Black MM: Nodular prurigo – a clinicopathological study of 46 patients. Br J Dermatol 1985;113:431–439.
8 Hong WW, Ang LW, Cutter JL, James L, Chew SK, Goh KT: Changing seroprevalence of hepatitis B virus markers of adults in Singapore. Ann Acad Med Singapore 2010; 39: 591–598. 9 Perez GL, Peters MS, Reda AM, Butterfield JH, Peterson EA, Leiferman KM: Mast cells, neutrophils and eosinophils in prurigo nodularis. Arch Dermatol 1993;129:861–865. 10 Bonacini M: Pruritus in patients with chronic human immunodeficiency virus, hepatitis B and C virus infections. Dig Liver Dis 2000;32: 621–625.
Note to the Readers
The publisher is well aware of the special nature of the paper entitled ‘Diagnostic Features of Pemphigus vulgaris in Patients with Bullous Pemphigoid: Molecular Analysis of Autoantibody Profile’ by Sami et al. [Dermatology 2002;204:108–117, DOI: 10.1159/000051827]. Everything possible has been undertaken in order to correctly modify the authorship. However, due to various reasons this proved to be an impossible task. The publisher therefore decided that the authorship of this article needs to remain as it is.
280
Dermatology 2014;228:276–280 DOI: 10.1159/000358250
Tan/Tey
