Tlio habitual use of opium is

by

no

means

confined

as

a

preventive of malarious fever

to

Godavery. Dr. Moore, Superintendent-General of Dispensaries, Rnjputana, has repeatedly drawn attention to the subject. In his report on the Rajputana Dispensaries for the year 1871 lie observes : ?

much attention to

the influence of

opium-eat"Having paid ing on the natives of this country, I may be permited to express an opinion that, however it may be in China and elsewhere, the habit of consuming opium is not here followed by those dire OPIUM AS A

PROPHYLACTIC

MALARIOUS

OF

consequences which sensational writers would have a large quantity of opium will kill ; and in

us

believe. Of

excessive, but not quickly poisonous, doses, ill-health, terminating in the opium djscrasy, marked by apathy, debility, and diarrhoea, will supercourse

FEVERS.

Dr. Cobnish, Sanitary Commissioner for Madras, not long ago drew the attention of his Government to the great consumpvene. But this is no worse than the results of immoderate use tion of opium in the Godavery district. An investigation was of alcoholic liquors, and I feel sure that quite as much misery ordered, and Mr. Foster, in the report from which we have given

long

a

extract in the

preceding article, furnishes the following information on the subject " Opium is very largely imported into the Godavery District from the Nizam's dominions via Jnggayyapeta; indeed, I believe that very little of the large amount used in the district comes from any other source. Malwa opium is largely used, but that also coines through the Nizam's dominions. A slight quantity is exported to Vizagapatam and other places north. Prom a!l the inquiries I have made, I am led to believe that the value of the drug used comes to no less than seven lakhs of rupees per annum. It is used by persons of both sexes, the least estimate being that forty per cent, of the male population and twenty-five per cent, of the female population are opium-eaters, other estimates amounting to as much as seventyfire per cent, amongst males and fifty per cent, amongst females. All classes of society use it indiscriminately, but the use amongst Brahmins and Yuisyas is not so extensive as amongst the other classes. I

am

satisfied that it is not used

only

indulgence. It stages, especially rife in this

as

an

is considered a cure for several diseases in their final

preventive against some diseases After steady use for a time it is found so difficult to break through the habit, that persons who have once taken it and

a

district.

seldom leave off. There

are

several indications that the drug is used which I may mention the

following

as a

:?

medicine, amongst (1.) It is given in small doses to children. (2.) It is not used as a rule by healthy adults before the a^e of thirty or forty, indicating that it is not taken as a source of pleasure. (3.) It is not so much used by the upper classes as the lower, indicating again that it is not taken as a self-indulgence> but is considered necessury to those living a life of greater exposure and less abundantly supplied with clothing and good

are produced by the latter as by the immoderate use as with And, opium. alcohol, so with opium, the moderate use of the drug is, notwithstanding all advanced against it, often actually beneficial. The use of opium enables the "kossid" to travel long distances, which, without such stimulant, he would be unable to accomplish. Opium affords endurance to persons who, in the semi-desert districts of Marwar, either tending camels, or otherwise, are reduced to Remittent and Intermittent fever, Indian Annals of living on the most meagre fare, Medical Science, No. XXI. and the least nourishing of cereals. And, as I have elsewhere* observed, I am inclined to believe that opium exerts a prophylactic influence over the occurrence of I have frequently noticed the confirmed malarious disease. opium-eaters escape fever when others were attacked. This was specially noticed during tile autumn following the heavy rains of 1863. At Joudpoor, in the month of October, every two opiumperson attached to the Political Agency, excepting eaters, suffered from one or other type of fever. Many natives, moreover, believe opium will not only preserve them The drug has from fever, but also from some other maladies. indeed long been regarded as a remedial agent, second only to quinine, and therefore a prophylactic action might be presumed. Besides, like alcohol, preventing waste of tissue, it also exerts its well-known, direct, stimulating or sedative influ*

the nervous system, and thus tends to prevent malapoison taking effect in several different ways. Lastly, there are numerous old persons met with, who, hale and ence

The drug is considered an admirable febrifuge and is administered to fever-patients. It is supposed to keep out cold and prevent rheumatism and ague. I believe that the extensive use of

opium in this district is due to the extensive prevalence of fever, and that if the fever could be checked so would the use of the drug. Conversely, I think it unadvisable to at

present."

attempt arbitrarily

to

stop its

con-

on

rious

hearty, have been addicted to opium-eating during the greater portion of their lives. The conclusion appears, therefore, inevitable that the abuse, not the moderate use, of opium must be credited with the undoubted deleterious results of immoderate indulgence in the practice of either eating or

smoking

the

drug."

has

Opium tion with

frequently

quinine

been used both alone and in combina-

in the treatment

of malarious fevers.

It

by Paracelsus in doses of thirty, forty or fifty minims of the tinctui-e exhibited an hour before the expected paroxysm. Lind recommended the administration of the drug during the hot stage and applied an opium liniment to the

was

houses.

sumption

and disease

of

recommended

spine one

on

the

approach

The use of narcotine, opium, as an antiperiodic was O'Shaughnessy and its virtues have

of the cold stage.

of the constituents of

introduced by Sir W.

The most careful and been proved by several observers. complete trial of this drug was made by Dr. A. Garden

THE INDIAN MEDICAL GAZETTE.

218 during an epidemic

of fever at

Ghazeepore

in 1859-60.

The

results of his experience were published in Yol. VII of the Indian Annals of Medical Science. He concluded that " though not of equal value with q\iinine, it has just claim to the next place in the ranks of antiperiodics and that there is no drug (quinine excepted) which cures so rapidly, so surely and with of the drug itself, at the same time that so little expenditure it is free from disagreeable effects in the majority of cases." Such being the case, the prophylactic value of opium becomes intelligible, though its use for the purpose of preventing fever can hardly, on other grounds, be recommended.

[August 1,

1874.

Opium as a Prophylactic of Malarious Fevers.

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