JACC: CARDIOVASCULAR INTERVENTIONS

VOL. 8, NO. 5, 2015

ª 2015 BY THE AMERICAN COLLEGE OF CARDIOLOGY FOUNDATION

ISSN 1936-8798/$36.00

PUBLISHED BY ELSEVIER INC.

http://dx.doi.org/10.1016/j.jcin.2014.11.027

IMAGES IN INTERVENTION

Overestimation of Paravalvular Leak With Edwards SAPIEN 3 Transcatheter Aortic Valve Replacement Taisei Kobayashi, MD, Jay Giri, MD, MPH, Prashanth Vallabhajosyula, MD, Howard C. Herrmann, MD, Dinesh H. Jagasia, MD

A

n 88-year-old woman with a history of

Transthoracic echocardiography performed the next

severe aortic stenosis presented for a trans-

day suggested severe PVL based on a >30% circum-

aortic valve replacement (TAVR). A pre-

ferential extent of PVL in the parasternal short-axis

TAVR computed tomography angiogram showed

(PSAX) view obtained just above the level of the

an aortic annular area of 385 mm 2 and an average

skirt of the SAPIEN 3 valve (Figure 1C, Online Video 2).

diameter of 22.1 mm (Figure 1A). The patient under-

However, the apical 3-chamber view and PSAX view

went an uncomplicated transfemoral #23 SAPIEN 3

obtained just below the level of the skirt showed only

valve

(Edwards

Lifesciences,

Irvine,

California)

implantation.

mild PVL (Figure 1D, Online Video 3 and Figure 1E, Online Video 4). The prominent circumferential dia-

The presence of a paravalvular leak (PVL) after

stolic color flow signal noted in the aortic root (at and

TAVR may be associated with increased mortality (1).

above the skirt of the SAPIEN 3 valve) may lead to

However, the assessment of paravalvular aortic

overestimation

regurgitation (AR) after TAVR is challenging. One

assessment of PVL must be done from multiple views.

of the widely used criteria for grading a PVL suggested

The evaluation of the circumferential extent of PVL

by the Valve Academic Research Consortium (VARC-2)

must be carefully performed below the aortic annulus

uses the circumferential extent of the prosthetic valve

and the skirt of the SAPIEN 3 valve to avoid over-

PVL (i.e.,

Overestimation of paravalvular leak with Edwards SAPIEN 3 transcatheter aortic valve replacement.

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