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Oxygen Saturation Target Range for Extremely Preterm Infants A Systematic Review and Meta-analysis Veena Manja, MD; Satyan Lakshminrusimha, MD; Deborah J. Cook, MSc, MD Editorial page 311 IMPORTANCE The optimal oxygen saturation (SpO2) target for extremely preterm infants is

unknown. OBJECTIVE To systematically review evidence evaluating the effect of restricted vs liberal oxygen exposure on morbidity and mortality in extremely preterm infants.

Journal Club Slides and Supplemental content at jamapediatrics.com CME Quiz at jamanetworkcme.com and CME Questions page 411

DATA SOURCES MEDLINE, PubMed, CENTRAL, and CINAHL databases from their inception to March 31, 2014, and abstracts submitted to Pediatric Academic Societies from 2000 to 2014. STUDY SELECTION All published randomized trials evaluating the effect of restricted (SpO2, 85%-89%) vs liberal (SpO2, 91%-95%) oxygen exposure in preterm infants (

Oxygen saturation target range for extremely preterm infants: a systematic review and meta-analysis.

The optimal oxygen saturation (SpO2) target for extremely preterm infants is unknown...
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