5(2)S8-42 MED.,OURNAL;l N{ALAWI 2OO3 JUNE.
meningitis patientoutcomein adultswith pneumococcal admittedto QECH or bacteraemia StephenB Gordon TrustClinicalResearchProgramme,Blantyre.Email:sgordon@mlw'medcol'mw Malawi-Liverpool-Wellcome
ABSTRACT Pneumococcal infections are common in Malawian adults' We set out to determine which factors influence in-hospital mortality and long-term survival among these patients' Features of history and examination, inpatient mortality and long-term survival were described among consecutively admitted QECH patients with S. pneumoniae in blood or CSF. 217 patients with pneumococcal diseasewere studied over an L8-month period. Among these, 158 of 167 consenting to testing (95Vo) were HIV positive. Inpatient mortality was 65Vo for pneumococcal meningitis (n=64), 20Vo for pneumococcaemic pneumonia (n=92) and 267o for patients
with pneumococcaemia without localising signs (n=43)' Lowered consciouslevel (OR 5.8, p
meningitis patientoutcomein adultswith pneumococcal admittedto QECH or bacteraemia StephenB Gordon TrustClinicalResearchProgramme,Blantyre.Email:sgordon@mlw'medcol'mw Malawi-Liverpool-Wellcome
ABSTRACT Pneumococcal infections are common in Malawian adults' We set out to determine which factors influence in-hospital mortality and long-term survival among these patients' Features of history and examination, inpatient mortality and long-term survival were described among consecutively admitted QECH patients with S. pneumoniae in blood or CSF. 217 patients with pneumococcal diseasewere studied over an L8-month period. Among these, 158 of 167 consenting to testing (95Vo) were HIV positive. Inpatient mortality was 65Vo for pneumococcal meningitis (n=64), 20Vo for pneumococcaemic pneumonia (n=92) and 267o for patients
with pneumococcaemia without localising signs (n=43)' Lowered consciouslevel (OR 5.8, p
