Clin Chem Lab Med 2014; 52(12): e283–e285
Letter to the Editor Nasser E. Ajubi*, Jesmine Kross-Brion and Cora J. Newton
Performance characteristics of the enzymatic Abbott Architect HbA1c whole blood assay Keywords: diabetes mellitus; hemoglobin A1c (HbA1c); hemoglobinopathy. DOI 10.1515/cclm-2014-0061 Received January 16, 2014; accepted May 25, 2014; previously published online June 24, 2014
To the Editor, Diabetes mellitus (DM) has a high worldwide prevalence. Multiple laboratory tests are available to manage patients with DM. Hemoglobin A1c (HbA1c) is widely used as an aid in the diagnosis of DM and for the long-term monitoring of blood glucose control. Several method types (each with its limitations) are used to measure HbA1c: immunoassay, ion-exchange high performance liquid chromatography (HPLC), boronate affinity HPLC and more recently enzymatic assays. Current guidelines for HbA1c testing mandate that HbA1c assays show tight analytical specifications (
Letter to the Editor Nasser E. Ajubi*, Jesmine Kross-Brion and Cora J. Newton
Performance characteristics of the enzymatic Abbott Architect HbA1c whole blood assay Keywords: diabetes mellitus; hemoglobin A1c (HbA1c); hemoglobinopathy. DOI 10.1515/cclm-2014-0061 Received January 16, 2014; accepted May 25, 2014; previously published online June 24, 2014
To the Editor, Diabetes mellitus (DM) has a high worldwide prevalence. Multiple laboratory tests are available to manage patients with DM. Hemoglobin A1c (HbA1c) is widely used as an aid in the diagnosis of DM and for the long-term monitoring of blood glucose control. Several method types (each with its limitations) are used to measure HbA1c: immunoassay, ion-exchange high performance liquid chromatography (HPLC), boronate affinity HPLC and more recently enzymatic assays. Current guidelines for HbA1c testing mandate that HbA1c assays show tight analytical specifications (
