Heart, Lung and Circulation (2014) 23, 385–386 1443-9506/04/$36.00 http://dx.doi.org/10.1016/j.hlc.2013.11.010

LETTER TO THE EDITOR

PFO Closure Following Tricuspid Valve-in-Valve Implantation Keywords

Patent foramen ovale  TAVI  Valve-in-valve  Tricuspid valve  Percutaneous  Transcatheter

The case of a 60 year-old woman who underwent successful tricuspid valve-in-valve implantation for an early degenerated bioprosthesis was previously described [1]. After 14 months of well-being the patient experienced once again exertional dyspnoea. Clinical examination was unremarkable: there were neither heart murmurs nor peripheral oedema. A cardiopulmonary test showed mild depression of functional capacity (VO2 peak of 19.7 ml/kg/min, 85% of the theoretical expected value), and moderate desaturation (SO2 88% after four minutes). At the transthoracic echocardiogram the Sapien XT prosthesis in tricuspid position was found to have a mean gradient of 4 mmHg, and minimal, physiological, central regurgitation (Fig. 1A). A bubble-contrast showed a rightto-left shunt at rest, through a patent foramen ovale (PFO)

(Fig. 1B). We therefore decided to proceed with percutaneous closure of the PFO. Intra-procedural cavography (308 left anterior oblique projection) confirmed the right-to-left shunt (Fig. 2A). The mean right atrial pressure was 6 mmHg. The PFO was easily closed with a 9-025-PFO Amplatzer (Fig. 2B). The following day her arterial saturation measured after climbing four flights of stairs remained normal at 98% and the patient was discharged. The cardiopulmonary test, performed nine months after the PFO closure, showed a normal functional capacity (VO2 peak of 21.8 ml/kg/min, 94% of the theoretical expected value) and no desaturation (SO2 97% at the end of the test with a minimum of 94% at the stress peak). This case shows that even after successful right heart surgery, a PFO can allow a right-to-left shunt of sufficient

Fig. 1 Transthoracic echocardiography (A) perfect functioning of the Sapien XT prosthesis in tricuspid position with a mean gradient of 4 mmHg and (B) bubble contrast in the left cavities.

© 2013 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier Inc. All rights reserved.

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S. Salizzoni et al.

Fig. 2 (A) The white arrow points to contrast through the formaen ovale during the cavography. (B) Final result after the Amplatzer deployment.

magnitude as to provoke dyspnoea [2]. Under such circumstances, therefore, a PFO should be systematically searched for and, if present, closed. Stefano Salizzoni* Fulvio Orzan Mauro Rinaldi University of Torino, Citta` della Salute e della Scienza ‘‘Molinette’’, Department of Surgical Sciences, Corso Bramante 88, 10126 Torino, Italy *Corresponding author. Tel.: +39 011 6335511; fax: +39 011 6336130. Emails: [email protected], [email protected] (S. Salizzoni)

Received 21 October 2013; received in revised form 18 November 2013; accepted 19 November 2013; online published-ahead-of-print 28 November 2013

References [1] Salizzoni S, La Torre M, Barbero C, Marra WG, Moretti C, D’Amico M, et al. Transjugular tricuspid valve-in-valve implantation. Heart Lung Circ 2013;(May). http://dx.doi.org/10.1016/j.hlc.2013.04.113. pii:S1443-9506 (13)00323-5 [Epub ahead of print]. [2] Oakley CM, Braimbridge MV, Bentall HH, Cleland WP. Reversed interatrial shunt following complete relief of pulmonary valve stenosis. Br Heart J 1964;26:662–70.

PFO closure following tricuspid valve-in-valve implantation.

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