EUROPEAN JOURNAL OF DRUG METABOUSM AND PHARMACOKINETICS, 1990, Vol. IS, No. I, pp. 1-5

Pharmacokinetics of vinpocetine and it~ main metabolite apovincaminic acid before and after the chronic oral administration of vinpocetine to humans P. MISKOLCZI, K. KOZMA, M. POLGAR, L. VERECZKEY Department ofPharmacokinetics and DrugMetabolism, Chemical Works ofGedeon RichterLtd, Budapest, Hungary

Received for publication: February 2, 1988

Keywords: Pharmacokinetics, vinpocetine apovincaminic acid, healthy volunteers

SUMMARY The pharmacokinetics of vinpocetine (Cavinton

Pharmacokinetics of vinpocetine and its main metabolite apovincaminic acid before and after the chronic oral administration of vinpocetine to humans.

The pharmacokinetics of vinpocetine (Cavinton) and of its main metabolite apovincaminic acid (AVA), has been studied in 5 healthy male volunteers afte...
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