Clinical Endocrinology (1991)34,463-467
Plasma growth hormone (GH)-releasing hormone levels in patients with lung carcinoma Jochen Schopohl, Marco Losa*, Chris Frey, Gernot Wolfram, Rudolf Huber, Wllllbald Permanetter, Joachlm von Pawel, 0. Albrecht MOller and Klaus von Werder Klinikum Innenstadt, Medizinische Klinik and Pathologisches Institut, University of Munich; Pneumologische Abteilung, Zentralkrankenhaus Gauting; and Schloppark-Klinik, Free University of Berlin; FR Germany (Received 4 July 1990; returned for revision 3 September 1990; finally revised 14 January 1991; accepted 4 February 1991)
Summary OBJECTlVEThe aim was to Investigatethe serum levels of growth hormone releasing hormone and GH In patients with lung carcinoma. DESIGN After an overnight fast a plasma sample was collected for determination of growth hormone releasing hormone and GH. PATIENTS The Investigation was performed In 28 patients with non small cell lung carcinoma, In 44 patients with small cell lung carcinoma, and 10 patients with non malignant lung disease. A group of 37 normal subjects served as control. MEASUREMENTS Growth hormone releasing hormone and GH were determined by radlolmmunoassay. RESULTS Patients with small cell lung carcinoma showed higher plasma growth hormone releasing hormone levels (49*9.4 ngll) than control subjects (16.3f2.1 ngll; P
Plasma growth hormone (GH)-releasing hormone levels in patients with lung carcinoma Jochen Schopohl, Marco Losa*, Chris Frey, Gernot Wolfram, Rudolf Huber, Wllllbald Permanetter, Joachlm von Pawel, 0. Albrecht MOller and Klaus von Werder Klinikum Innenstadt, Medizinische Klinik and Pathologisches Institut, University of Munich; Pneumologische Abteilung, Zentralkrankenhaus Gauting; and Schloppark-Klinik, Free University of Berlin; FR Germany (Received 4 July 1990; returned for revision 3 September 1990; finally revised 14 January 1991; accepted 4 February 1991)
Summary OBJECTlVEThe aim was to Investigatethe serum levels of growth hormone releasing hormone and GH In patients with lung carcinoma. DESIGN After an overnight fast a plasma sample was collected for determination of growth hormone releasing hormone and GH. PATIENTS The Investigation was performed In 28 patients with non small cell lung carcinoma, In 44 patients with small cell lung carcinoma, and 10 patients with non malignant lung disease. A group of 37 normal subjects served as control. MEASUREMENTS Growth hormone releasing hormone and GH were determined by radlolmmunoassay. RESULTS Patients with small cell lung carcinoma showed higher plasma growth hormone releasing hormone levels (49*9.4 ngll) than control subjects (16.3f2.1 ngll; P
