Clinical Science (1992) 83, 737 (Printed in Great Britain)
737
Corremondence
Platelet angiotensin II receptors in pregnancy M. PAWLAK and G. MACDONALD Department of Nephrology, School of Medicine, Prince Henry Hospital, Little Bay, NS W 2036, Australia (Received 24 July 1992)
In a recent paper by Baker et al. (Clin. Sci. 1992; 82, 377-81) [l], reference was made to our study of platelet angiotensin I1 receptors in normal and hypertensive pregnancy (reference 13 in [l]). We wish to point out that the authors have incorrectly suggested that we conducted a cross-sectional rather
than a longitudinal study. In fact, we studied a group of normal pregnant women in early gestation and then followed up the same group in the third trimester. We observed subsequent development of pregnancy-induced hypertension in two subjects who had shown significantly higher angiotensin I1 binding than the rest of the third-trimester group. The findings of our study were published in full in the August 1992 issue of the Journal of Hypertension
PI. REFERENCES I. Baker, P.N., Broughton, Pipkin F. & Symonds, E.M. Longitudinal study of platelet angiotensin I1 binding in human pregnancy. Clin. Sci. 1992; 82, 37741. 2. Pawlak, M.A. & Macdonald, G.J. Altered number of platelet angiotensin I1 receptors in relation to plasma agonist concentration in normal and hypertensive pregnancy. J. Hypertens. 1992; 10, 813-19.
737
Corremondence
Platelet angiotensin II receptors in pregnancy M. PAWLAK and G. MACDONALD Department of Nephrology, School of Medicine, Prince Henry Hospital, Little Bay, NS W 2036, Australia (Received 24 July 1992)
In a recent paper by Baker et al. (Clin. Sci. 1992; 82, 377-81) [l], reference was made to our study of platelet angiotensin I1 receptors in normal and hypertensive pregnancy (reference 13 in [l]). We wish to point out that the authors have incorrectly suggested that we conducted a cross-sectional rather
than a longitudinal study. In fact, we studied a group of normal pregnant women in early gestation and then followed up the same group in the third trimester. We observed subsequent development of pregnancy-induced hypertension in two subjects who had shown significantly higher angiotensin I1 binding than the rest of the third-trimester group. The findings of our study were published in full in the August 1992 issue of the Journal of Hypertension
PI. REFERENCES I. Baker, P.N., Broughton, Pipkin F. & Symonds, E.M. Longitudinal study of platelet angiotensin I1 binding in human pregnancy. Clin. Sci. 1992; 82, 37741. 2. Pawlak, M.A. & Macdonald, G.J. Altered number of platelet angiotensin I1 receptors in relation to plasma agonist concentration in normal and hypertensive pregnancy. J. Hypertens. 1992; 10, 813-19.
