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Geriatr Gerontol Int 2014
ORIGINAL ARTICLE: EPIDEMIOLOGY, CLINICAL PRACTICE AND HEALTH
Polypharmacy and health outcomes among older adults discharged from hospital: Results from the CRIME study Federica Sganga,1 Francesco Landi,1 Carmelinda Ruggiero,2 Andrea Corsonello,3 Davide L Vetrano,1 Fabrizia Lattanzio,4 Antonio Cherubini,5 Roberto Bernabei1 and Graziano Onder1 1
Department of Gerontology, Neuroscience and Orthopedics, Catholic University of the Sacred Heart, Rome, 2Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Perugia, 3Unit of Geriatric Pharmacoepidemiology, Italian National Research Center on Aging (INRCA), Cosenza, 4Scientific Direction, and 5Department of Geriatrics, Italian National Research Center on Aging (INRCA), Ancona, Italy
Aim: To investigate if older adults using multiple drugs have an increased risk of rehospitalization and mortality after hospital discharge. Methods: This was a prospective cohort study carried out in acute care hospitals. The primary outcomes of the study were rehospitalization and mortality within 1 year after discharge from acute care hospitals. The study population was categorized in two groups according to the number of drugs prescribed at hospital discharge: no polypharmacy (