www.scielo.br/jaos http://dx.doi.org/10.1590/1678-775720160092
Porosity of temporary denture soft liners containing antifungal agents Jozely Francisca Mello LIMA1, Janaína Gomes MACIEL1, Juliana HOTTA1, Ana Carolina Pero VIZOTO2, Heitor Marques HONÓRIO3, Vanessa Migliorini URBAN4, Karin Hermana NEPPELENBROEK1
1- Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Prótese, Bauru, SP, Brasil. 2- Universidade Estadual Paulista, Faculdade de Odontologia de Araraquara, Departamento de Materiais Odontológicos e Prótese, Araraquara, SP, Brasil. 3- Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Odontopediatria, Ortodontia e Saúde Coletiva, Bauru, SP, Brasil. 4- Universidade Estadual de Ponta Grossa, Departamento de Odontologia, Ponta Grossa, PR, Brasil. Corresponding address: Karin Hermana Neppelenbroek - Al. Octávio Pinheiro Brisola, 9-75 - Bauru - SP - 17012-901 - Brazil - Phone: +55 14 3235 8245 - Fax: +55 14 3235 8277 - e-mail: [email protected] 6XEPLWWHG )HEUXDU\ 0RGL¿FDWLRQ $SULO$FFHSWHG $SULO
ABSTRACT
I
ncorporation of antifungals in temporary denture soft liners has been recommended for denture stomatitis treatment; however, it may affect their properties. Objective: To evaluate the porosity of a tissue conditioner (Softone) and a temporary resilient liner 7UXVRIW PRGL¿HGE\PLQLPXPLQKLELWRU\FRQFHQWUDWLRQV 0,&V RIDQWLIXQJDODJHQWVIRU Candida albicans ELR¿OP 0DWHULDO DQG 0HWKRGV 7KH SRURVLW\ ZDV PHDVXUHG E\ ZDWHU absorption, based on exclusion of the plasticizer effect. Initially, it was determined by sorption isotherms that the adequate storage solution for specimens (65x10x3.3 mm) of both materials was 50% anhydrous calcium chloride (S50). Then, the porosity factor (PF) was calculated for the study groups (n=10) formed by specimens without (control) or with drug incorporation at MICs (nystatin:Ny-0.032 g, chlorhexidine diacetate: Chx0.064 g, or ketoconazole: Ke-0.128 g each per gram of soft liner powder) after storage in distilled water or S50 for 24 h, seven and 14 d. Data were statistically analyzed by 4-way repeated measures ANOVA and Tukey’s test (D=.05). Results: Ke resulted in no VLJQL¿FDQWFKDQJHVLQ3)IRUERWKOLQHUVLQZDWHURYHUGD\V S! &RPSDUHGZLWK the controls, Softone and Trusoft PFs were increased at 14-day water immersion only after addition of Ny and Chx, and Chx, respectively (p
Porosity of temporary denture soft liners containing antifungal agents Jozely Francisca Mello LIMA1, Janaína Gomes MACIEL1, Juliana HOTTA1, Ana Carolina Pero VIZOTO2, Heitor Marques HONÓRIO3, Vanessa Migliorini URBAN4, Karin Hermana NEPPELENBROEK1
1- Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Prótese, Bauru, SP, Brasil. 2- Universidade Estadual Paulista, Faculdade de Odontologia de Araraquara, Departamento de Materiais Odontológicos e Prótese, Araraquara, SP, Brasil. 3- Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Odontopediatria, Ortodontia e Saúde Coletiva, Bauru, SP, Brasil. 4- Universidade Estadual de Ponta Grossa, Departamento de Odontologia, Ponta Grossa, PR, Brasil. Corresponding address: Karin Hermana Neppelenbroek - Al. Octávio Pinheiro Brisola, 9-75 - Bauru - SP - 17012-901 - Brazil - Phone: +55 14 3235 8245 - Fax: +55 14 3235 8277 - e-mail: [email protected] 6XEPLWWHG )HEUXDU\ 0RGL¿FDWLRQ $SULO$FFHSWHG $SULO
ABSTRACT
I
ncorporation of antifungals in temporary denture soft liners has been recommended for denture stomatitis treatment; however, it may affect their properties. Objective: To evaluate the porosity of a tissue conditioner (Softone) and a temporary resilient liner 7UXVRIW PRGL¿HGE\PLQLPXPLQKLELWRU\FRQFHQWUDWLRQV 0,&V RIDQWLIXQJDODJHQWVIRU Candida albicans ELR¿OP 0DWHULDO DQG 0HWKRGV 7KH SRURVLW\ ZDV PHDVXUHG E\ ZDWHU absorption, based on exclusion of the plasticizer effect. Initially, it was determined by sorption isotherms that the adequate storage solution for specimens (65x10x3.3 mm) of both materials was 50% anhydrous calcium chloride (S50). Then, the porosity factor (PF) was calculated for the study groups (n=10) formed by specimens without (control) or with drug incorporation at MICs (nystatin:Ny-0.032 g, chlorhexidine diacetate: Chx0.064 g, or ketoconazole: Ke-0.128 g each per gram of soft liner powder) after storage in distilled water or S50 for 24 h, seven and 14 d. Data were statistically analyzed by 4-way repeated measures ANOVA and Tukey’s test (D=.05). Results: Ke resulted in no VLJQL¿FDQWFKDQJHVLQ3)IRUERWKOLQHUVLQZDWHURYHUGD\V S! &RPSDUHGZLWK the controls, Softone and Trusoft PFs were increased at 14-day water immersion only after addition of Ny and Chx, and Chx, respectively (p
