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Letters to the Editor To the Editor: I would like to comment on the report by Oreamuno et al., Comparative Clinical Study of Porous Hydroxyapatite and Decalcified Freeze-Dried Bone in Human Periodontal Defects (JPeriodontol 1990;61:399-404). While I thought the report provided useful information regarding the clinical response to two commonly-used bone graft materials, I was more interested in what the report did not provide, the type of statistical tests used. The most important missing information concerns the depths of the original bony defects and, by extension, the percentage of defect fill obtained as a result of therapy. According to the Materials and Methods, the investigators collected the defect depth measurements at both the initial and the reentry surgery, but chose not to report those findings. Instead, they reported the mm of defect fill only. While this information is useful, it has no real meaning or clinical relevance unless it is combined with the original defect depth measurements to determine the percent of defect fill. For instance, their finding of almost 3.5 mm mean defect fill with PHA would be meaningful if the original bony defects were 4.0 mm deep (87% fuTjÇ but not so impressive if the original bony defects were 10 mm deep .
.
The comments in the Letter to the Editor are important and we hope that our response clarifies the data presented in the paper.— Silvia Oreamuno, E. Barrie Kenney, and Fermín A. Carranza, UCLA, Los Angeles, CA. To the Editor: re:
Allergic
Contact Dermatitis and Latex Gloves
.
(35% fill)_
.1 propose that reporting of the original defect depth should be a requirement in bone graft and regeneration studies, especially when these data were collected as part of the protocol. ..—Raymond A. Yukna, Denver, CO. ...
.
Authors' Response: We appreciate the opportunity to respond to the letter concerning our paper. The measurements of bony defects were made from a grooved acrylic stent and hence only changes were reported. However, the extent of the bony defects can be assumed from presurgical measurement of the level of the alveolar crest and the level of the depth of the bony defect. The following details the data from Center A. The mean difference between the alveolar crest and defect measurement was initially 5.00 mm for the porous hydroxyapatite (PHA) group and 4.70 mm for the decalcified freezedried bone (DFDB) group. This would give a 65% fill of the original defect with PHA and 49.6% fill with DFDB.
study has reported that 7.4% of physicians in operating units were allergic to latex gloves (Turjanmaa K, Reunala T, Contact urticaria from rubber gloves, Dermatol Clin 1988;6:47-51). In practice, the incidence of latex contact dermatitis is probably higher, since it is presumed that a significant number of cases have been underreported due to physician self diagnosis and self medication (Maso MJ, Goldberg DJ, Contact dermatoses from disposable glove A recent
A review, J Am Acad Dermatol 1990;23:733-7). Another report contains information which may be of benefit to a significant number of clinicians and patients who routinely utilize, or are subjected to, disposable latex gloves (Rich P, Belozer ML, Norris P, Storrs FJ, Allergic contact dermatitis to two antioxidants in latex gloves: 4,4'-thiobis(6tert-butyl-meta-cresol) '(Lowinox 44S36) and butylhydroxyanisole, J Am Acad Dermatol 1991;24:37-43). These authors describe two instances of allergic contact dermatitis which developed on the hands and face of patients after exposure to latex. Although both patients were patch test negative for common latex rubber allergens, each patient was positive for antioxidants used in the manufacture of some brands of latex. In an attempt to obtain gloves which could be safely worn by these patients, the authors compiled lists of ingredients from glove manufacturers. These data provided information from which appropriate patient recommendations could be made. A table listing the presence of 7 common antigens in 30 individual glove types were generated during the course of this study, and was presented in detail in the paper. The data presented by Rich et al. could be of considerable value to periodontists wishing to obtain latex examination gloves free of specific allergens. Robert E. Cohen and Mirdza E. Neiders, State University of New York, Buffalo, NY. use:
Letters to the Editor To the Editor: I would like to comment on the report by Oreamuno et al., Comparative Clinical Study of Porous Hydroxyapatite and Decalcified Freeze-Dried Bone in Human Periodontal Defects (JPeriodontol 1990;61:399-404). While I thought the report provided useful information regarding the clinical response to two commonly-used bone graft materials, I was more interested in what the report did not provide, the type of statistical tests used. The most important missing information concerns the depths of the original bony defects and, by extension, the percentage of defect fill obtained as a result of therapy. According to the Materials and Methods, the investigators collected the defect depth measurements at both the initial and the reentry surgery, but chose not to report those findings. Instead, they reported the mm of defect fill only. While this information is useful, it has no real meaning or clinical relevance unless it is combined with the original defect depth measurements to determine the percent of defect fill. For instance, their finding of almost 3.5 mm mean defect fill with PHA would be meaningful if the original bony defects were 4.0 mm deep (87% fuTjÇ but not so impressive if the original bony defects were 10 mm deep .
.
The comments in the Letter to the Editor are important and we hope that our response clarifies the data presented in the paper.— Silvia Oreamuno, E. Barrie Kenney, and Fermín A. Carranza, UCLA, Los Angeles, CA. To the Editor: re:
Allergic
Contact Dermatitis and Latex Gloves
.
(35% fill)_
.1 propose that reporting of the original defect depth should be a requirement in bone graft and regeneration studies, especially when these data were collected as part of the protocol. ..—Raymond A. Yukna, Denver, CO. ...
.
Authors' Response: We appreciate the opportunity to respond to the letter concerning our paper. The measurements of bony defects were made from a grooved acrylic stent and hence only changes were reported. However, the extent of the bony defects can be assumed from presurgical measurement of the level of the alveolar crest and the level of the depth of the bony defect. The following details the data from Center A. The mean difference between the alveolar crest and defect measurement was initially 5.00 mm for the porous hydroxyapatite (PHA) group and 4.70 mm for the decalcified freezedried bone (DFDB) group. This would give a 65% fill of the original defect with PHA and 49.6% fill with DFDB.
study has reported that 7.4% of physicians in operating units were allergic to latex gloves (Turjanmaa K, Reunala T, Contact urticaria from rubber gloves, Dermatol Clin 1988;6:47-51). In practice, the incidence of latex contact dermatitis is probably higher, since it is presumed that a significant number of cases have been underreported due to physician self diagnosis and self medication (Maso MJ, Goldberg DJ, Contact dermatoses from disposable glove A recent
A review, J Am Acad Dermatol 1990;23:733-7). Another report contains information which may be of benefit to a significant number of clinicians and patients who routinely utilize, or are subjected to, disposable latex gloves (Rich P, Belozer ML, Norris P, Storrs FJ, Allergic contact dermatitis to two antioxidants in latex gloves: 4,4'-thiobis(6tert-butyl-meta-cresol) '(Lowinox 44S36) and butylhydroxyanisole, J Am Acad Dermatol 1991;24:37-43). These authors describe two instances of allergic contact dermatitis which developed on the hands and face of patients after exposure to latex. Although both patients were patch test negative for common latex rubber allergens, each patient was positive for antioxidants used in the manufacture of some brands of latex. In an attempt to obtain gloves which could be safely worn by these patients, the authors compiled lists of ingredients from glove manufacturers. These data provided information from which appropriate patient recommendations could be made. A table listing the presence of 7 common antigens in 30 individual glove types were generated during the course of this study, and was presented in detail in the paper. The data presented by Rich et al. could be of considerable value to periodontists wishing to obtain latex examination gloves free of specific allergens. Robert E. Cohen and Mirdza E. Neiders, State University of New York, Buffalo, NY. use:
