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International Journal of Urology (2014) 21, 894–898
doi: 10.1111/iju.12465
Original Article: Clinical Investigation
Predictors of positive surgical margins and their location in Korean men undergoing radical prostatectomy Min Soo Choo,1 Sung Yong Cho,2 Chang Wook Jeong,1 Seung Bae Lee,2 Ja Hyeon Ku,1 Sung Kyu Hong,3 Seok-Soo Byun,3 Cheol Kwak,1 Hyeon Hoe Kim,1 Sang Eun Lee3 and Hyeon Jeong2 1 Department of Urology, Seoul National University Hospital, 2Department of Urology, Seoul National University Boramae Hospital, Seoul, and 3Department of Urology, Seoul National University Bundang Hospital, Seongnam, Korea
Abbreviations & Acronyms +AM = positive apical margin +BM = positive basal margin +MM = positive multifocal margin +PLM = positive posterolateral margin −SM = negative surgical margin BCR = biochemical recurrence GS = Gleason scores LRP = laparoscopic radical prostatectomy MM = multifocal margin ORP = open radical prostatectomy PCa = prostate cancer PL = posterolateral PSA = prostate-specific antigen PSM = positive surgical margins RALP = robotic-assisted laparoscopic radical prostatectomy RP = radical prostatectomy Correspondence: Hyeon Jeong M.D., Ph.D., Department of Urology, Seoul National University Boramae Hospital, Sindaebang 2-dong, 395 Dongjak-gu, Seoul 156-707, Korea. Email: [email protected] Received 8 October 2013; accepted 17 March 2014. Online publication 8 May 2014
894
Objective: To evaluate preoperative predictors of positive surgical margins and their location in Korean men undergoing radical prostatectomy. Methods: A total of 3227 patients who had undergone radical prostatectomy (open, robotic or laparoscopic) for clinically localized prostate cancer at three centers between 2000 and 2010 were analyzed. Patients were stratified by using the D’Amico risk criteria. Positive surgical margins were categorized according to their location. Patients were divided depending on their prostate volume: 20 or cT2c-T3a stage or GS 8–10).10 PSM, defined as cancer cells reaching the inked surface of the specimen, were categorized into four groups according to the following locations: apex, base, posterolateral and multifocal. The prostate volume was measured by preoperative transrectal ultrasonography according to the prolate ellipsoid formula (π/6 × D3). The patients were divided into four equal quadrants depending on their prostate volume:
International Journal of Urology (2014) 21, 894–898
doi: 10.1111/iju.12465
Original Article: Clinical Investigation
Predictors of positive surgical margins and their location in Korean men undergoing radical prostatectomy Min Soo Choo,1 Sung Yong Cho,2 Chang Wook Jeong,1 Seung Bae Lee,2 Ja Hyeon Ku,1 Sung Kyu Hong,3 Seok-Soo Byun,3 Cheol Kwak,1 Hyeon Hoe Kim,1 Sang Eun Lee3 and Hyeon Jeong2 1 Department of Urology, Seoul National University Hospital, 2Department of Urology, Seoul National University Boramae Hospital, Seoul, and 3Department of Urology, Seoul National University Bundang Hospital, Seongnam, Korea
Abbreviations & Acronyms +AM = positive apical margin +BM = positive basal margin +MM = positive multifocal margin +PLM = positive posterolateral margin −SM = negative surgical margin BCR = biochemical recurrence GS = Gleason scores LRP = laparoscopic radical prostatectomy MM = multifocal margin ORP = open radical prostatectomy PCa = prostate cancer PL = posterolateral PSA = prostate-specific antigen PSM = positive surgical margins RALP = robotic-assisted laparoscopic radical prostatectomy RP = radical prostatectomy Correspondence: Hyeon Jeong M.D., Ph.D., Department of Urology, Seoul National University Boramae Hospital, Sindaebang 2-dong, 395 Dongjak-gu, Seoul 156-707, Korea. Email: [email protected] Received 8 October 2013; accepted 17 March 2014. Online publication 8 May 2014
894
Objective: To evaluate preoperative predictors of positive surgical margins and their location in Korean men undergoing radical prostatectomy. Methods: A total of 3227 patients who had undergone radical prostatectomy (open, robotic or laparoscopic) for clinically localized prostate cancer at three centers between 2000 and 2010 were analyzed. Patients were stratified by using the D’Amico risk criteria. Positive surgical margins were categorized according to their location. Patients were divided depending on their prostate volume: 20 or cT2c-T3a stage or GS 8–10).10 PSM, defined as cancer cells reaching the inked surface of the specimen, were categorized into four groups according to the following locations: apex, base, posterolateral and multifocal. The prostate volume was measured by preoperative transrectal ultrasonography according to the prolate ellipsoid formula (π/6 × D3). The patients were divided into four equal quadrants depending on their prostate volume:
![[Positive surgical margins after radical prostatectomy].](/assets/img/hold.png)
