ORIGINAL ARTICLE
Pretreatment neutrophil-to-lymphocyte ratio as predictor of survival for patients with metastatic nasopharyngeal carcinoma Ying Jin, MD,1 Xiao Ye, MD,2 Chunxiao He, MD,1 Beibei Zhang, MD,1 Yiping Zhang, MD1* 1
Department of Medical Oncology, Zhejiang Cancer Hospital, Hangzhou, China, 2Department of Endocrinology, Zhejiang Provincial People’s Hospital, Hangzhou, China.
Accepted 5 December 2013 Published online 00 Month 2013 in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/hed.23565
ABSTRACT: Background. The outcomes of patients with metastatic nasopharyngeal carcinoma (NPC) differ between individuals. The purpose of this study was to examine the impact of neutrophil-to-lymphocyte ratio (NLR) on survival in patients with metastatic NPC. Methods. A total of 229 patients with disseminated NPC were evaluated. The effects of pretreatment peripheral blood neutrophil, lymphocyte, and NLR on survival were examined using the proportional hazards regression model to estimate hazard ratio (HR). The relationship between short-term treatment efficacy and pretreatment NLR was analyzed using the chi-square test.
INTRODUCTION Nasopharyngeal carcinoma (NPC) is a disease with a remarkable ethnic and geographic distribution worldwide. Although the incidence of NPC is very low (
Pretreatment neutrophil-to-lymphocyte ratio as predictor of survival for patients with metastatic nasopharyngeal carcinoma Ying Jin, MD,1 Xiao Ye, MD,2 Chunxiao He, MD,1 Beibei Zhang, MD,1 Yiping Zhang, MD1* 1
Department of Medical Oncology, Zhejiang Cancer Hospital, Hangzhou, China, 2Department of Endocrinology, Zhejiang Provincial People’s Hospital, Hangzhou, China.
Accepted 5 December 2013 Published online 00 Month 2013 in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/hed.23565
ABSTRACT: Background. The outcomes of patients with metastatic nasopharyngeal carcinoma (NPC) differ between individuals. The purpose of this study was to examine the impact of neutrophil-to-lymphocyte ratio (NLR) on survival in patients with metastatic NPC. Methods. A total of 229 patients with disseminated NPC were evaluated. The effects of pretreatment peripheral blood neutrophil, lymphocyte, and NLR on survival were examined using the proportional hazards regression model to estimate hazard ratio (HR). The relationship between short-term treatment efficacy and pretreatment NLR was analyzed using the chi-square test.
INTRODUCTION Nasopharyngeal carcinoma (NPC) is a disease with a remarkable ethnic and geographic distribution worldwide. Although the incidence of NPC is very low (
