ORIGINAL PAPER

Prevalence of renal dysfunction in ischaemic stroke and transient ischaemic attack patients with or without atrial fibrillation M. Laiblea,*, S. Horstmanna,*, T. Rizosa, G. Rauchb, M. Zornc and R. Veltkampa,d a

Department of Neurology, University of Heidelberg, Heidelberg,Germany; bInstitute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg,Germany; cDepartment of Internal Medicine – I, University of Heidelberg, Heidelberg, Germany; and d Department of Stroke Medicine, Imperial College London, London, UK

EUROPEAN JOURNAL OF NEUROLOGY

Keywords:

atrial fibrillation, oral anticoagulation, renal function impairment, stroke Received 7 April 2014 Accepted 9 June 2014 European Journal of Neurology 2015, 22: 64–69 doi:10.1111/ene.12528

Background and purpose: Chronic kidney disease (CKD) is associated with a higher risk of stroke and atrial fibrillation (AF). There are limited data on the comorbidity of renal dysfunction and AF in stroke patients. Our aim was to determine the frequency of kidney dysfunction in ischaemic stroke patients with and without AF. Methods: In a prospectively collected, single center cohort of acute ischaemic stroke and transient ischaemic attack (TIA) patients, glomerular filtration rate (eGFR) was estimated using the Modification of Diet in Renal Disease equation on admission. Renal function was graded into five categories (cat.): cat. 1, eGRF ≥90 ml/min/1.73 m2; cat. 2, 60–89; cat. 3, 30–59; cat. 4, 15–29; cat. 5,

Prevalence of renal dysfunction in ischaemic stroke and transient ischaemic attack patients with or without atrial fibrillation.

Chronic kidney disease (CKD) is associated with a higher risk of stroke and atrial fibrillation (AF). There are limited data on the comorbidity of ren...
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