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irnmz~nolog),lode3, Oclober 198t
Primary structures of transplantation antigens The complete primary structure of a murine H-2K b molecule has recently been described by Nathenson and colleagues 1. Partial sequences for several other H-2 molecules are known, and in the human system nearly complete primary sequences are available for HLA-B7 and HLA-A2 molecules 2. These sequences have been obtained, often laboriously, directly from protein sequencing techniques. Indeed, the primarysequence oftheH-2Kbmolecule is the firstprotein sequence to have been determined entirely by radiosequencing methods. However, the isolation of c D N A clones encoding mouse 3,4 and human 5,
irnmz~nolog),lode3, Oclober 198t
Primary structures of transplantation antigens The complete primary structure of a murine H-2K b molecule has recently been described by Nathenson and colleagues 1. Partial sequences for several other H-2 molecules are known, and in the human system nearly complete primary sequences are available for HLA-B7 and HLA-A2 molecules 2. These sequences have been obtained, often laboriously, directly from protein sequencing techniques. Indeed, the primarysequence oftheH-2Kbmolecule is the firstprotein sequence to have been determined entirely by radiosequencing methods. However, the isolation of c D N A clones encoding mouse 3,4 and human 5,
