REVIEW
Prognosis After Acute Myocardial Infarction: Relation to Blood Pressure Values Before Infarction in a Prospective Cardiovascular Study
SIMON W. RABKIN, MD, FRCP(C), FACC FRANCIS A. L. MATHEWSON, MD, FACC ROBERT B. TATE, MSc Winnipeg, Manitoba, Canada
From the Departments of Medicine (Section of Cardiology) and Social and Preventive Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. This study was supported in part by a grant from Department of Health and Welfare, Ottawa, Ontario, Canada. Manuscript received April 27, 1977, accepted May 18, 1977. Address for reprints: Simon W. Rabkin, MD, Manitoba Follow-up Study, Faculty of Medicine, University of Manitoba, 770 Bannatyne Avenue, Winnipeg, Manitoba, Canada R3E 0W3.
604
October 1977
The relation of preexisting hypertension to survival after myocardial infarction is uncertain, but it has been examined primarily in studies with limited data on previous blood pressure values. Therefore in the Manitoba Study cohort, 3,983 men under observation since 1948, the last recorded blood pressure before the first myocardial infarction as well as the change in blood pressure from a measurement made 5 years previously was related to survival after the infarction. With use of the life table method, progressively increasing values for systolic or diastolic blood pressure were found to be associated with worsening prognosis. Subjects with a systolic pressure of 140 mm Hg or greater or a diastolic pressure of 90 mm Hg or greater had a significantly (P
Prognosis After Acute Myocardial Infarction: Relation to Blood Pressure Values Before Infarction in a Prospective Cardiovascular Study
SIMON W. RABKIN, MD, FRCP(C), FACC FRANCIS A. L. MATHEWSON, MD, FACC ROBERT B. TATE, MSc Winnipeg, Manitoba, Canada
From the Departments of Medicine (Section of Cardiology) and Social and Preventive Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. This study was supported in part by a grant from Department of Health and Welfare, Ottawa, Ontario, Canada. Manuscript received April 27, 1977, accepted May 18, 1977. Address for reprints: Simon W. Rabkin, MD, Manitoba Follow-up Study, Faculty of Medicine, University of Manitoba, 770 Bannatyne Avenue, Winnipeg, Manitoba, Canada R3E 0W3.
604
October 1977
The relation of preexisting hypertension to survival after myocardial infarction is uncertain, but it has been examined primarily in studies with limited data on previous blood pressure values. Therefore in the Manitoba Study cohort, 3,983 men under observation since 1948, the last recorded blood pressure before the first myocardial infarction as well as the change in blood pressure from a measurement made 5 years previously was related to survival after the infarction. With use of the life table method, progressively increasing values for systolic or diastolic blood pressure were found to be associated with worsening prognosis. Subjects with a systolic pressure of 140 mm Hg or greater or a diastolic pressure of 90 mm Hg or greater had a significantly (P
