Heart Vessels DOI 10.1007/s00380-015-0670-4
ORIGINAL ARTICLE
Prognostic significance of late gadolinium enhancement quantification in cardiac magnetic resonance imaging of hypertrophic cardiomyopathy with systolic dysfunction Akira Funada1 · Hideaki Kanzaki1 · Teruo Noguchi1 · Yoshiaki Morita2 · Yasuo Sugano1 · Takahiro Ohara1 · Takuya Hasegawa1 · Hiromi Hashimura2,3 · Hatsue Ishibashi‑Ueda3 · Masafumi Kitakaze1,4 · Satoshi Yasuda1 · Hisao Ogawa1 · Toshihisa Anzai1 Received: 18 December 2014 / Accepted: 20 March 2015 © Springer Japan 2015
Abstract Hypertrophic cardiomyopathy (HCM) with systolic dysfunction carries a poor prognosis. Although late gadolinium enhancement (LGE) on cardiac magnetic resonance is associated with adverse cardiac events in HCM and is inversely related to left ventricular ejection fraction (LVEF), it is unknown whether LGE or LVEF more accurately predicts adverse cardiac events in HCM with systolic dysfunction. We retrospectively assessed the extent of LGE with a threshold of 6 standard deviations in 46 consecutive HCM patients with systolic dysfunction defined as LVEF
ORIGINAL ARTICLE
Prognostic significance of late gadolinium enhancement quantification in cardiac magnetic resonance imaging of hypertrophic cardiomyopathy with systolic dysfunction Akira Funada1 · Hideaki Kanzaki1 · Teruo Noguchi1 · Yoshiaki Morita2 · Yasuo Sugano1 · Takahiro Ohara1 · Takuya Hasegawa1 · Hiromi Hashimura2,3 · Hatsue Ishibashi‑Ueda3 · Masafumi Kitakaze1,4 · Satoshi Yasuda1 · Hisao Ogawa1 · Toshihisa Anzai1 Received: 18 December 2014 / Accepted: 20 March 2015 © Springer Japan 2015
Abstract Hypertrophic cardiomyopathy (HCM) with systolic dysfunction carries a poor prognosis. Although late gadolinium enhancement (LGE) on cardiac magnetic resonance is associated with adverse cardiac events in HCM and is inversely related to left ventricular ejection fraction (LVEF), it is unknown whether LGE or LVEF more accurately predicts adverse cardiac events in HCM with systolic dysfunction. We retrospectively assessed the extent of LGE with a threshold of 6 standard deviations in 46 consecutive HCM patients with systolic dysfunction defined as LVEF
