Gaudry et al. Ann. Intensive Care (2017) 7:21 DOI 10.1186/s13613-017-0235-z
Open Access
RESEARCH
Prone positioning in acute respiratory distress syndrome after abdominal surgery: a multicenter retrospective study SAPRONADONF (Study of Ards and PRONe position After abDOmiNal surgery in France) Stéphane Gaudry1,2, Samuel Tuffet1,3,4, Anne‑Claire Lukaszewicz3,4, Christian Laplace5, Noémie Zucman1, Marc Pocard6,7, Bruno Costaglioli8, Simon Msika9,10, Jacques Duranteau5, Didier Payen3,4, Didier Dreyfuss1,11,12, David Hajage2,13 and Jean‑Damien Ricard1,11,12,14*
Abstract Background: The recent demonstration of prone position’s strong benefit on patient survival has rendered proning a major therapeutic intervention in severe ARDS. Uncertainties remain as to whether or not ARDS patients in the postoperative period of abdominal surgery should be turned prone because of the risk of abdominal complications. Our aim was to investigate the prevalence of surgical complications between patients with and without prone position after abdominal surgery. Methods: This study was a multicenter retrospective cohort of patients with ARDS in a context of recent abdominal surgery. Primary outcome was the number of patients who had at least one surgical complication that could be induced or worsened by prone position. Secondary outcomes included effects of prone position on oxygenation. Data from the prone group were compared with those from the supine group (not having undergone at least a prone position session). Results: Among 98 patients included, 36 (37%) had at least one prone position session. The rate of surgical complications induced or worsened by prone position did not differ between prone and supine groups [respectively, 14 (39%) vs 27 (44%); p = 0.65]. After propensity score application, there was no significant difference between the two groups (OR 0.72 [0.26–2.02], p = 0.54). Revision surgery did not differ between the groups. The first prone session significantly increased PaO2/FiO2 ratio from 95 ± 47 to 189 ± 92 mmHg, p
Open Access
RESEARCH
Prone positioning in acute respiratory distress syndrome after abdominal surgery: a multicenter retrospective study SAPRONADONF (Study of Ards and PRONe position After abDOmiNal surgery in France) Stéphane Gaudry1,2, Samuel Tuffet1,3,4, Anne‑Claire Lukaszewicz3,4, Christian Laplace5, Noémie Zucman1, Marc Pocard6,7, Bruno Costaglioli8, Simon Msika9,10, Jacques Duranteau5, Didier Payen3,4, Didier Dreyfuss1,11,12, David Hajage2,13 and Jean‑Damien Ricard1,11,12,14*
Abstract Background: The recent demonstration of prone position’s strong benefit on patient survival has rendered proning a major therapeutic intervention in severe ARDS. Uncertainties remain as to whether or not ARDS patients in the postoperative period of abdominal surgery should be turned prone because of the risk of abdominal complications. Our aim was to investigate the prevalence of surgical complications between patients with and without prone position after abdominal surgery. Methods: This study was a multicenter retrospective cohort of patients with ARDS in a context of recent abdominal surgery. Primary outcome was the number of patients who had at least one surgical complication that could be induced or worsened by prone position. Secondary outcomes included effects of prone position on oxygenation. Data from the prone group were compared with those from the supine group (not having undergone at least a prone position session). Results: Among 98 patients included, 36 (37%) had at least one prone position session. The rate of surgical complications induced or worsened by prone position did not differ between prone and supine groups [respectively, 14 (39%) vs 27 (44%); p = 0.65]. After propensity score application, there was no significant difference between the two groups (OR 0.72 [0.26–2.02], p = 0.54). Revision surgery did not differ between the groups. The first prone session significantly increased PaO2/FiO2 ratio from 95 ± 47 to 189 ± 92 mmHg, p
