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MALE AND FEMALE SEXUAL FUNCTION AND DYSFUNCTION; ANDROLOGY
such as small corporotomies, drain placement, careful 3-layer skin closure and submuscular reservoir placement. Allen F. Morey, MD
Re: Inflatable Penile Prosthesis Technique and Outcomes after Radial Forearm Free Flap Neophalloplasty R. L. Segal, E. Z. Massanyi, A. D. Gupta, J. P. Gearhart, R. J. Redett, T. J. Bivalacqua and A. L. Burnett James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Division of Pediatric Urology, Charlotte Bloomberg Children’s Hospital, and Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland Int J Impot Res 2014; Epub ahead of print.
Abstract for this article http://dx.doi.org/10.1016/j.juro.2014.12.057 available at http://jurology.com/ Editorial Comment: These authors are to be commended for reporting their experience with inflatable penile prosthesis (IPP) insertion in men with a neophallus. Mean patient age was 23.6 years (range 18 to 31), and mean interval from neophalloplasty to IPP implantation was 22.1 months (3 to 48). In all cases 3-piece IPPs were used, with 8 of the patients having 1 cylinder implanted in the native corporeal body and extending into the neophallus. Mean surgical time was 222 minutes (range 142 to 409). Median length of implanted device was 22 cm. No intraoperative complications were observed. At the most recent followup 6 patients (66.7%) had functional devices with acceptable surgical outcomes. Three patients (33.3%) sustained device infections and 3 (33.3%) sustained cylinder erosion. These are challenging cases. It is noteworthy that these cases were performed at a specialty center. Allen D. Seftel, MD
Suggested Reading Garaffa G, Spilotros M, Christopher NA et al: Total phallic reconstruction using radial artery based forearm free flap phalloplasty in patients with epispadiasexstrophy complex. J Urol 2014; 192: 814.
Re: Regional Cerebral Blood Flow following Single-Dose and Continuous-Dose Tadalafil after Stroke M. Lorberboym, E. Makhline and Y. Lampl Department of Nuclear Medicine, Edith Wolfson Medical Center, Holon and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Acta Neurol Scand 2014; 130: 380e386.
Abstract for this article http://dx.doi.org/10.1016/j.juro.2015.01.052 available at http://jurology.com/ Editorial Comment: The purpose of this study was to explore the effect of a single, on demand dose of tadalafil compared to low dose continuous administration on regional cerebral blood flow (rCBF) in patients after stroke. A total of 30 consecutive male patients (mean SD age 58.3 7.9 years) with erectile dysfunction and a history of stroke were included in the study. Baseline single-photon emission computerized tomography (SPECT) was performed 15 minutes after administration of 740 MBq 99mtechnetium hexamethylpropyleneamine oxime intravenously. Of the patients 15 were randomized to receive a single dose of 20 mg tadalafil in the morning and to undergo a second SPECT 6 hours later. The remaining 15 patients received 5 mg tadalafil each morning for 7 consecutive days and underwent the second SPECT 6 hours after the last dose. All patients showed areas of reduced relative rCBF in the affected hemisphere after tadalafil administration compared to baseline (p
MALE AND FEMALE SEXUAL FUNCTION AND DYSFUNCTION; ANDROLOGY
such as small corporotomies, drain placement, careful 3-layer skin closure and submuscular reservoir placement. Allen F. Morey, MD
Re: Inflatable Penile Prosthesis Technique and Outcomes after Radial Forearm Free Flap Neophalloplasty R. L. Segal, E. Z. Massanyi, A. D. Gupta, J. P. Gearhart, R. J. Redett, T. J. Bivalacqua and A. L. Burnett James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Division of Pediatric Urology, Charlotte Bloomberg Children’s Hospital, and Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland Int J Impot Res 2014; Epub ahead of print.
Abstract for this article http://dx.doi.org/10.1016/j.juro.2014.12.057 available at http://jurology.com/ Editorial Comment: These authors are to be commended for reporting their experience with inflatable penile prosthesis (IPP) insertion in men with a neophallus. Mean patient age was 23.6 years (range 18 to 31), and mean interval from neophalloplasty to IPP implantation was 22.1 months (3 to 48). In all cases 3-piece IPPs were used, with 8 of the patients having 1 cylinder implanted in the native corporeal body and extending into the neophallus. Mean surgical time was 222 minutes (range 142 to 409). Median length of implanted device was 22 cm. No intraoperative complications were observed. At the most recent followup 6 patients (66.7%) had functional devices with acceptable surgical outcomes. Three patients (33.3%) sustained device infections and 3 (33.3%) sustained cylinder erosion. These are challenging cases. It is noteworthy that these cases were performed at a specialty center. Allen D. Seftel, MD
Suggested Reading Garaffa G, Spilotros M, Christopher NA et al: Total phallic reconstruction using radial artery based forearm free flap phalloplasty in patients with epispadiasexstrophy complex. J Urol 2014; 192: 814.
Re: Regional Cerebral Blood Flow following Single-Dose and Continuous-Dose Tadalafil after Stroke M. Lorberboym, E. Makhline and Y. Lampl Department of Nuclear Medicine, Edith Wolfson Medical Center, Holon and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Acta Neurol Scand 2014; 130: 380e386.
Abstract for this article http://dx.doi.org/10.1016/j.juro.2015.01.052 available at http://jurology.com/ Editorial Comment: The purpose of this study was to explore the effect of a single, on demand dose of tadalafil compared to low dose continuous administration on regional cerebral blood flow (rCBF) in patients after stroke. A total of 30 consecutive male patients (mean SD age 58.3 7.9 years) with erectile dysfunction and a history of stroke were included in the study. Baseline single-photon emission computerized tomography (SPECT) was performed 15 minutes after administration of 740 MBq 99mtechnetium hexamethylpropyleneamine oxime intravenously. Of the patients 15 were randomized to receive a single dose of 20 mg tadalafil in the morning and to undergo a second SPECT 6 hours later. The remaining 15 patients received 5 mg tadalafil each morning for 7 consecutive days and underwent the second SPECT 6 hours after the last dose. All patients showed areas of reduced relative rCBF in the affected hemisphere after tadalafil administration compared to baseline (p
