Biochem. J. (1979) 184, 345-354 Printed in Great Britain
345
Relationship of Prostaglandin Secretion by Rabbit Alveolar Macrophages to Phagocytosis and Lysosomal Enzyme Release By Wei HSUEH,*tt Charles KUHN, III* and Philip NEEDLEMAN§ *Department ofPathology and §Department ofPharmacology, Washington University, St. Louis, MO
63110, U.S.A., and tDepartment ofPathology, Northwestern University, Chicago, IL 60614, U.S.A. (Received 25 April 1979)
The phospholipids of rabbit alveolar macrophages were pulse-labelled with [14C]arachidonic acid, and the subsequent release of labelled prostaglandins was measured. Resting macrophages released measurable amounts of arachidonic acid, the prostaglandins E2, D2 and F2
345
Relationship of Prostaglandin Secretion by Rabbit Alveolar Macrophages to Phagocytosis and Lysosomal Enzyme Release By Wei HSUEH,*tt Charles KUHN, III* and Philip NEEDLEMAN§ *Department ofPathology and §Department ofPharmacology, Washington University, St. Louis, MO
63110, U.S.A., and tDepartment ofPathology, Northwestern University, Chicago, IL 60614, U.S.A. (Received 25 April 1979)
The phospholipids of rabbit alveolar macrophages were pulse-labelled with [14C]arachidonic acid, and the subsequent release of labelled prostaglandins was measured. Resting macrophages released measurable amounts of arachidonic acid, the prostaglandins E2, D2 and F2
