EXPERIMENTAL AND THERAPEUTIC MEDICINE 14: 841-847, 2017
Sesamol attenuates oxidative stress, apoptosis and inflammation in focal cerebral ischemia/reperfusion injury XIU‑JUAN GAO1,2*, GUAN‑NAN XIE2*, LEI LIU1,2, ZHI‑JIAN FU1, ZONG‑WANG ZHANG2 and LIANG‑ZHU TENG3 1
Department of Pain Management, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021; 2 Department of Anesthesiology, Liaocheng People's Hospital, Liaocheng, Shandong 252000; 3 Department of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China Received September 30, 2015; Accepted November 21, 2016 DOI: 10.3892/etm.2017.4550
Abstract. The aim of the present study was to evaluate the therapeutic potential of sesamol treatment on focal ischemia/reperfusion (I/R) injury in the rat brain. The results demonstrated that pretreatment with sesamol seven days prior to focal cerebral I/R injury had significant positive effects, including improvements in neurological deficits (P
Sesamol attenuates oxidative stress, apoptosis and inflammation in focal cerebral ischemia/reperfusion injury XIU‑JUAN GAO1,2*, GUAN‑NAN XIE2*, LEI LIU1,2, ZHI‑JIAN FU1, ZONG‑WANG ZHANG2 and LIANG‑ZHU TENG3 1
Department of Pain Management, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021; 2 Department of Anesthesiology, Liaocheng People's Hospital, Liaocheng, Shandong 252000; 3 Department of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China Received September 30, 2015; Accepted November 21, 2016 DOI: 10.3892/etm.2017.4550
Abstract. The aim of the present study was to evaluate the therapeutic potential of sesamol treatment on focal ischemia/reperfusion (I/R) injury in the rat brain. The results demonstrated that pretreatment with sesamol seven days prior to focal cerebral I/R injury had significant positive effects, including improvements in neurological deficits (P
