GRAY MATTERS doses of antiepileptic drugs (AEDs), and sleep deprivation, sometimes in combination. The discrepancy between uncontrolled seizures and treatment-resistant epilepsy3 was worthily addressed, and the need for educational intervention concerning preventable seizure precipitants was emphasized. In the Singapore study, noncompliance was defined as self-reported failure to take the correct AED dose within a week prior to admission.2 Our study was based on therapeutic drug monitoring (TDM). Nonadherence was defined as an AED concentration/dose ratio of
