© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Clin Transplant 2015: 29: 763–770 DOI: 10.1111/ctr.12577
Clinical Transplantation
Right ventricular failure after implantation of continuous flow left ventricular assist device: analysis of predictors and outcomes Lo C, Murphy D, Summerhayes R, Quayle M, Burrell A, Bailey M, Marasco SF. Right ventricular failure after implantation of continuous flow left ventricular assist device: analysis of predictors and outcomes.
Casey Loa,b, Deirdre Murphyc, Robyn Summerhayesa, Margaret Quaylea, Aiden Burrellc, Michael Baileyd and Silvana F. Marascoa,b a
Abstract: Postoperative right ventricular failure is a serious complication for up to 50% of patients following LVAD insertion. Predicting RV failure is an important factor for patients as planned BiVAD support has been shown to correlate with better outcomes compared to delayed BiVAD to LVAD conversion. This retrospective study examined prospectively collected data for 101 patients implanted with an LVAD between 2003 and 2013, aiming to establish preoperative predictive factors for RVF postLVAD insertion, analyze outcomes, and validate existing RVF scoring systems. In our cohort, 63 patients (62.4%) developed RV failure and consequently demonstrated consistently poorer survival throughout the follow-up period (log-rank p = 0.01). Multivariable logistic regression identified two significant variables: cardiac index mild Tricuspid regurgitation ≥ moderate Tricuspid regurgitation ≥ severe Mitral regurgitation > mild Right heart catheter data Cardiac output (L/min, inclusive of all supports) Cardiac index Cardiac index
Clin Transplant 2015: 29: 763–770 DOI: 10.1111/ctr.12577
Clinical Transplantation
Right ventricular failure after implantation of continuous flow left ventricular assist device: analysis of predictors and outcomes Lo C, Murphy D, Summerhayes R, Quayle M, Burrell A, Bailey M, Marasco SF. Right ventricular failure after implantation of continuous flow left ventricular assist device: analysis of predictors and outcomes.
Casey Loa,b, Deirdre Murphyc, Robyn Summerhayesa, Margaret Quaylea, Aiden Burrellc, Michael Baileyd and Silvana F. Marascoa,b a
Abstract: Postoperative right ventricular failure is a serious complication for up to 50% of patients following LVAD insertion. Predicting RV failure is an important factor for patients as planned BiVAD support has been shown to correlate with better outcomes compared to delayed BiVAD to LVAD conversion. This retrospective study examined prospectively collected data for 101 patients implanted with an LVAD between 2003 and 2013, aiming to establish preoperative predictive factors for RVF postLVAD insertion, analyze outcomes, and validate existing RVF scoring systems. In our cohort, 63 patients (62.4%) developed RV failure and consequently demonstrated consistently poorer survival throughout the follow-up period (log-rank p = 0.01). Multivariable logistic regression identified two significant variables: cardiac index mild Tricuspid regurgitation ≥ moderate Tricuspid regurgitation ≥ severe Mitral regurgitation > mild Right heart catheter data Cardiac output (L/min, inclusive of all supports) Cardiac index Cardiac index
